GADD34 Antikörper (C-Term)

Produktnummer ABIN121667

Der Ziege Polyklonal anti-GADD34 Antikörper wird verwendet zum Nachweis von GADD34 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für GADD34 Antikörper (C-Term) (ABIN121667)

Target: GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser GADD34 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GADD34 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Affinity chromatography

Immunogen: Peptide sequence AAALDLSGRRG corresponding to the C-terminus of GADD34 (NP_055145)

Anwendungsinformationen

Applikationshinweise: Western Blot: 0.5 μg/mL - 2 μg/mL, this antibody detects a band of approximately 80-90 kDa in U937 cell lysates, an overnight incubation time of 12 hours is recommended for this antibody.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: TRIS buffered saline pH 7.3 containing 0.02 % Sodium Azide and 0.5 % Bovine Serum Albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Haltbarkeit: 12 months

Details zu GADD34

Target: GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))

Andere Bezeichnung: GADD34 / PPP1R15A

Hintergrund: GADD34 is a member of a group of genes whose transcript levels are increased in response to treatment with DNA damaging agents or conditions of stress. Induction of GADD34 by ionising radiation has been reported in some cell lines, regardless of p53 status. Reports suggest that GADD34 may be involved in signal transuction pathway controlling cell cycle arrest and/or apoptosis following DNA damage.Synonyms: Growth arrest and DNA damage-inducible protein GADD34, Myeloid differentiation primary response protein MyD116 homolog, Protein phosphatase 1 regulatory subunit 15A

Pathways: ER-Nucleus Signaling, Unfolded Protein Response