POLM Antikörper (AA 6-18)

Produktnummer ABIN117919

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch POLM in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für POLM Antikörper (AA 6-18) (ABIN117919)

Target: POLM (Polymerase (DNA Directed), mu (POLM))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-POLM Antikörper

Bindungsspezifität: AA 6-18

Sequenz: Peptide sequence: R-R-A-R-V-G-S-P-S-G-D-A-A-C

Spezifität: This is an affinity purified antibody produced by Immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.

Aufreinigung: Immunoaffinity chromatography.

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to aa 6-18 of Human POLM µ (DNA polymerase mu). POLM µ is a template-directed terminal deoxynucleotidetransferase that shows a preferential expression in proliferating lymphoid cells.

Anwendungsinformationen

Applikationshinweise: This affinity purified antibody has been tested for use in ELISA against the immunizingpeptide. Reactivity in other immunoassays is unknown. This product has been assayed byELISA against 0.1 μg of the immunizing peptide. A 1: 33,000 to 1: 135,000 dilution of the antibody is recommended for this assay.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 2.1 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Dilute only prior to immediate use. Avoid cycles of freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store vial at -20 °C prior to opening. Aliquot contents and freeze at -20 °C or below for extended storage. Centrifuge product if not completely clear after standing at room temperature. This product is stable for one month at 2-8 °C as an undiluted liquid.

Details zu POLM

Target: POLM (Polymerase (DNA Directed), mu (POLM))

Andere Bezeichnung: DNA Polymerase mu

Hintergrund: DNA ploymerase mu is a template directed terminal deoxynucleotidetransferase that shows a preferential expression in proliferating lymphoid cells. It seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.Synonyms: POLM, Pol Mu, Tdt-N, TdtN

Gen-ID: 27434

NCBI Accession: NP_037416

UniProt: Q9NP87

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response