Smooth Muscle Actin Antikörper (N-Term)

Produktnummer ABIN114404

Der Maus Monoklonal anti-Smooth Muscle Actin Antikörper wird verwendet zum Nachweis von Smooth Muscle Actin in Proben von Human, Ratte, Maus, Huhn, Kaninchen und Rind (Kuh). Er wurde validiert für IHC (p).

Kurzübersicht für Smooth Muscle Actin Antikörper (N-Term) (ABIN114404)

Target: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Reaktivität: Human, Ratte, Maus, Huhn, Kaninchen, Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Smooth Muscle Actin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 1A4-asm-1

Produktdetails anti-Smooth Muscle Actin Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody is specific to alpha-smooth isoform of actin. It reacts with smooth muscle cells of vessels and different parenchymes. The antibody does not cross-react with beta and gamma-cytoplasmic, alpha-sarcomeric and alpha-myocardial actin isoforms.
Cellular Localization: Cytoplasmic.

Aufreinigung: Purified

Immunogen: N-terminal decapeptide of alpha-smooth muscle Actin

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Formalin Fixed Paraffin Embedded Sections: Use Actin antibodyat 1/25-1/50 dilution in an ABC method for 30 minutes at room temperature. Recommended Positive Control: Leiomyoma.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu Smooth Muscle Actin

Target: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Hintergrund: Smooth muscle actin is expressed in normal smooth muscle and in myoepithelial cells, and also in tumours derived from these cells. Actins are involved in maintaining the structure and integrity of a cell, as well as cell motility. They are highly conserved proteins and make up the majority of the contractile apparatus. To date, six different actin isoforms have been described.Synonyms: ACTSA, ACTVS, Alpha-actin-2, Cell growth-inhibiting gene 46 protein

Gen-ID: 59

NCBI Accession: NP_001135417

UniProt: P62736

Pathways: Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development