Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) (Intracellular Domain) Antikörper

Antigen: Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1)

Synonyme: CX3CL1, DKFZp459K117, Cx3C-rs1, Scyd1-rs1, NTN, NTT, CXC3, CXC3C, SCYD1, ABCD-3, C3Xkine, fractalkine, neurotactin, CX3C, Cxc3, Scyd1, AB030188, AI848747, D8Bwg0439e, Cx3c

Epitope: Intracellular Domain

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN110564

Produktbeschreibung

Weitere Bezeichnung: Fractalkine (Intracellular Domain)

Format: Protein A purified, 0.1% sodium azide, Lyophilized

Beschreibung: Fractalkine, also known as neurotactin, is a membrane-bound CX3C chemokine. The mature protein is part of a 397-amino acid precursor and consists of a chemokine domain of 76 amino acids, a mucin stalk of 241 amino acids, a putative transmembrane domain of 18 amino acids, and an intracellular tail of 37 amino acids. Within the chemokine domain the first two cysteine residues are separated by 3 amino acids (CX3C). Fractalkine message is found in high abundance in the brain, kidney, lung and heart tissues. Fractalkine is chemotactic for monocytes and other leukocytes including NK cells, lymphocytes, and may play a role in brain inflammation.

Anwendungen

Lagerung: 4°C for short term storage or -20°C in small aliquots for long term storage. Avoid repeated freeze and thaw. Reconstitute to 1 mg/ml by adding 200 µl H2O

Beschränkungen: Nur für Forschungszwecke einsetzbar