anti-PYCARD (PYCARD) Antikörper

anti-PYD and CARD Domain Containing Antikörper (PYCARD)
Auf finden Sie aktuell 154 PYD and CARD Domain Containing (PYCARD) Antikörper von 18 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PYCARD Kits (8) und PYCARD Proteine (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 182 PYCARD Produkte verfügbar.
9130417A21Rik, Asc, asc1, CARD5, masc, TMS, TMS-1, TMS1, TNS1, zAsc, zgc:109874
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PYCARD 282817  

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Meistgesuchte Reaktivitäten zu anti-PYCARD (PYCARD) Antikörper

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anti-Human PYCARD Antikörper:

anti-Mouse (Murine) PYCARD Antikörper:

anti-Rat (Rattus) PYCARD Antikörper:

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Am meisten referenzierte anti-PYCARD Antikörper

  1. Human Monoclonal PYCARD Primary Antibody für IP, WB - ABIN1105662 : Norlén, Curry, Björkqvist, Maule, Cunningham, Hogg, Harriott, Johnston, Hutton, Håkanson: Cell-specific processing of chromogranin A in endocrine cells of the rat stomach. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001 (PubMed)
    Zeige alle 8 Referenzen für 1105662

  2. Human Polyclonal PYCARD Primary Antibody für WB - ABIN610691 : Auphan, DiDonato, Rosette, Helmberg, Karin: Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis. in Science (New York, N.Y.) 1995 (PubMed)
    Zeige alle 4 Referenzen für 610691

  3. Human Polyclonal PYCARD Primary Antibody für ICC, IF - ABIN4281803 : Yao, Carlson, Sun, Ma, Wolf, Minei, Zang: Mitochondrial ROS Induces Cardiac Inflammation via a Pathway through mtDNA Damage in a Pneumonia-Related Sepsis Model. in PLoS ONE 2015 (PubMed)
    Zeige alle 3 Referenzen für 4281803

  4. Human Monoclonal PYCARD Primary Antibody für FACS, IHC - ABIN4281806 : Peng, French, Tillman, Morgan, French: The inflammasome in alcoholic hepatitis: Its relationship with Mallory-Denk body formation. in Experimental and molecular pathology 2014 (PubMed)

  5. Human Polyclonal PYCARD Primary Antibody für WB - ABIN4281797 : Siraj, Hussain, Al-Rasheed, Ahmed, Bavi, Alsobhi, Al-Nuaim, Uddin, Al-Kuraya: Demethylation of TMS1 gene sensitizes thyroid cancer cells to TRAIL-induced apoptosis. in The Journal of clinical endocrinology and metabolism 2011 (PubMed)

  6. Human Polyclonal PYCARD Primary Antibody für IHC (p), IHC - ABIN257733 : Ohtsuka, Ryu, Minamishima, Macip, Sagara, Nakayama, Aaronson, Lee: ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway. in Nature cell biology 2004 (PubMed)

  7. Mouse (Murine) Polyclonal PYCARD Primary Antibody für WB - ABIN2780039 : Mariathasan, Newton, Monack, Vucic, French, Lee, Roose-Girma, Erickson, Dixit: Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. in Nature 2004 (PubMed)

Weitere Antikörper gegen PYCARD Interaktionspartner

Human PYD and CARD Domain Containing (PYCARD) Interaktionspartner

  1. besides its role in the inhibition of the NF-kappaB (zeige NFKB1 Antikörper) pathway, NLRC3 (zeige NLRC3 Antikörper) interferes with the assembly and activity of the NALP3 (zeige NLRP3 Antikörper) inflammasome complex by competing with ASC for pro-caspase-1 (zeige CASP1 Antikörper) binding

  2. ASC Induces Apoptosis via Activation of Caspase-9 (zeige CASP9 Antikörper) by Enhancing Gap Junction-Mediated Intercellular Communication.(

  3. These data revealed that cross-linking of ASC(PYD) filaments via ASC(CARD) mediates the assembly of ASC foci.

  4. Down-regulation of mRNA expression was found in cases in which CASP8 (zeige CASP8 Antikörper), TMS1 (zeige SERINC3 Antikörper) and DAPK (zeige DAPK1 Antikörper) were hypermethylated.

  5. loss of ASC driven tumor development is counterbalanced in the identical cell by the inhibition of pro-tumorigenic inflammation in the tumor cell itself

  6. the deubiquitinating enzyme USP50 (zeige USP50 Antikörper) binds to the ASC protein and subsequently regulates the inflammasome signaling pathway.

  7. ASC self-associates and binds NLRP3 (zeige NLRP3 Antikörper) PYD through equivalent protein regions, with higher binding affinity for the latter. These regions are located at opposite sides of the protein allowing multimeric complex formation previously shown in ASC PYD fibril assemblies.

  8. Our data identify RIPK3 (zeige RIPK3 Antikörper) and the ASC inflammasome as key tumor suppressors in AML (zeige RUNX1 Antikörper).

  9. The role of the danger signals ASC and HMGB1 (zeige HMGB1 Antikörper) in the Fusobacterium nucleatum infection of gingival epithelial cells.

  10. Data show that NOD-like receptor signaling genes NOD2 (zeige NOD2 Antikörper), PYCARD, CARD6 (zeige CARD6 Antikörper), and IFI16 (zeige IFI16 Antikörper) are upregulated in psoriatic epidermis.

Mouse (Murine) PYD and CARD Domain Containing (PYCARD) Interaktionspartner

  1. this study shows that ASC (zeige STS Antikörper)-dependent Inflammasomes do not shape the commensal gut (zeige GUSB Antikörper) microbiota composition

  2. Our data identify RIPK3 (zeige RIPK3 Antikörper) and the ASC (zeige STS Antikörper) inflammasome as key tumor suppressors in AML (zeige RUNX1 Antikörper).

  3. Data show that T cell-intrinsic PYD and CARD domain containing protein ASC is required for TH17-mediated experimental autoimmune encephalomyelitis (EAE).

  4. Data suggest that interleukin 22 (IL-22 (zeige IL22 Antikörper)) plays a pro-inflammatory/pathogenic role in the onset of antigen-induced arthritis (AIA) through apoptosis-associated speck-like Pycard protein (ASC (zeige STS Antikörper))-dependent stimulation of interleukin-1 beta (IL-1beta (zeige IL1B Antikörper)) production.

  5. report herein that lack of ASC (zeige STS Antikörper) does not confer preferential protection in response to P. aeruginosa acute infection and that ASC (zeige STS Antikörper)(-/-) mice are capable of producing robust amounts of IL-1beta (zeige IL1B Antikörper) comparable with C57BL/6 mice

  6. These data identify a novel non-canonical immunoregulatory function of NLRP3 (zeige NLRP3 Antikörper) and ASC (zeige STS Antikörper) in autoimmunity.

  7. a significant role for NLRP3 (zeige NLRP3 Antikörper) and ASC (zeige STS Antikörper) in prion (zeige PRNP Antikörper) pathogenesis

  8. ASC (zeige STS Antikörper)-driven caspase-1 (zeige CASP1 Antikörper) autoprocessing and speck formation are dispensable for the activation of caspase-1 (zeige CASP1 Antikörper) and the NLRP1b inflammasome.

  9. IKKalpha (zeige CHUK Antikörper) controls the inflammasome at the level of the adaptor molecule ASC (zeige STS Antikörper), which interacts with IKKalpha (zeige CHUK Antikörper) in the nucleus of resting macrophages in an IKKalpha (zeige CHUK Antikörper) kinase-dependent manner.

  10. Hypoxia-induced elevated right ventricular pressure and remodeling were attenuated in mice lacking the inflammasome adaptor protein ASC (zeige STS Antikörper), suggesting that inflammasomes play an important role in the pathogenesis of pulmonary hypertension.

PYCARD Antigen-Profil

Beschreibung des Gens

This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm\; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with PYCARD

  • PYD and CARD domain containing (PYCARD) Antikörper
  • PYD and CARD domain containing (Pycard) Antikörper
  • PYD and CARD domain containing (pycard) Antikörper
  • 9130417A21Rik Antikörper
  • Asc Antikörper
  • asc1 Antikörper
  • CARD5 Antikörper
  • masc Antikörper
  • TMS Antikörper
  • TMS-1 Antikörper
  • TMS1 Antikörper
  • TNS1 Antikörper
  • zAsc Antikörper
  • zgc:109874 Antikörper

Bezeichner auf Proteinebene für PYCARD

apoptosis-associated speck-like protein containing a CARD , caspase recruitment domain-containing protein 5 , target of methylation-induced silencing 1 , PYD and CARD domain-containing protein

29108 Homo sapiens
66824 Mus musculus
282817 Rattus norvegicus
282846 Bos taurus
57923 Danio rerio
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