anti-Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1) Antikörper

SIGLEC1 encodes a member of the immunoglobulin superfamily. Zusätzlich bieten wir Ihnen SIGLEC1 Kits (26) und SIGLEC1 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SIGLEC1 20612 Q62230
SIGLEC1 6614 Q9BZZ2
SIGLEC1 311426  
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Top anti-SIGLEC1 Antikörper auf antikoerper-online.de

Showing 10 out of 261 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert FACS, IHC (fro), IHC (p), in vitro, IHC, RIA, ELISA, WB Immunohistochemistry-Paraffin: Sialoadhesin Antibody (HSn 7D2) [ABIN153421] - IHC staining of Sialoadhesin in human spleen using DAB with hematoxylin counterstain. Flow Cytometry: Siglec-1/CD169 Antibody (HSn 7D2)  - Human CD14+ PBMC differentiated to M1 macrophages with rhGM-CSF were stained with Mouse Anti- Siglec-1/CD169 Monoclonal Antibody ( open histogram) followed by APC-conjugated Anti-Mouse IgG Secondary Antibody . 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
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Maus Ratte FITC FACS 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$797.50
Details
Maus Ratte Unkonjugiert CyTOF, FACS, WB Detection of Siglec-1/CD169 in RAW 264.7 Mouse Cell Line by Flow Cytometry. RAW 264.7 mouse monocyte/macrophage cell line was stained with Mouse Siglec-1/CD169 Monoclonal Antibody. Detection of Mouse Siglec-1/CD169 by Western Blot. Western blot shows lysates of mouse splenocytes. PVDF Membrane was probed with 1 ug/mL of Mouse Siglec-1/CD169 Monoclonal Antibody. This experiment was conducted under non-reducing conditions. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$262.50
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Maus Ratte Unkonjugiert FACS, IHC (fro), IF 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$346.50
Details
Maus Ratte Biotin IHC (fro)   0.2 mg Anmelden zum Anzeigen 6 bis 8 Tage
$709.50
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Maus Ratte PE FACS 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$273.00
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Maus Ratte Unkonjugiert FACS, IHC (fro)   0.2 mg Anmelden zum Anzeigen 6 bis 8 Tage
$621.50
Details
Human Maus Unkonjugiert CyTOF, FACS Detection of Siglec-1/CD169 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) either (A) untreated or (B) treated with 20 ng/mL Recombinant Human IFN-gamma. Detection of Siglec-1/CD169 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) either (A) untreated or (B) treated with 20 ng/mL Recombinant Human IFN-gamma. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$278.25
Details
Maus Ratte FITC FACS, IF   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$533.50
Details
Schwein Maus FITC FACS   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$753.50
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SIGLEC1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-SIGLEC1 Antikörper

  1. Human Monoclonal SIGLEC1 Primary Antibody für FACS, IHC (fro) - ABIN153421 : Hartnell, Steel, Turley, Jones, Jackson, Crocker: Characterization of human sialoadhesin, a sialic acid binding receptor expressed by resident and inflammatory macrophage populations. in Blood 2001 (PubMed)
    Show all 10 Pubmed References

  2. Mouse (Murine) Monoclonal SIGLEC1 Primary Antibody für IHC (fro), FACS - ABIN2478779 : Kadir: Balloon occlusion technique for renal venography. in RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin 1979 (PubMed)
    Show all 4 Pubmed References

  3. Mouse (Murine) Monoclonal SIGLEC1 Primary Antibody für FACS - ABIN2478776 : Kaisho, Takeda, Tsujimura, Kawai, Nomura, Terada, Akira: IkappaB kinase alpha is essential for mature B cell development and function. in The Journal of experimental medicine 2001 (PubMed)
    Show all 4 Pubmed References

  4. Mouse (Murine) Monoclonal SIGLEC1 Primary Antibody für IHC (fro), FACS - ABIN2478771 : Hughes, Schlichtenbrede, Murphy, Sarra, Luthert, Ali, Dick: Generation of activated sialoadhesin-positive microglia during retinal degeneration. in Investigative ophthalmology & visual science 2003 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal SIGLEC1 Primary Antibody für Func, IHC (f) - ABIN2749112 : Kawasaki, Vela, Nycholat, Rademacher, Khurana, van Rooijen, Crocker, Kronenberg, Paulson: Targeted delivery of lipid antigen to macrophages via the CD169/sialoadhesin endocytic pathway induces robust invariant natural killer T cell activation. in Proceedings of the National Academy of Sciences of the United States of America 2013 (PubMed)
    Show all 2 Pubmed References

  6. Pig (Porcine) Monoclonal SIGLEC1 Primary Antibody für IHC (fro), FACS - ABIN2478766 : Mitchell: Recessive oncogenes, antioncogenes and tumour suppression. in British medical bulletin 1991 (PubMed)
    Show all 4 Pubmed References

  7. Pig (Porcine) Monoclonal SIGLEC1 Primary Antibody für FACS - ABIN2478767 : Bullido, Gómez del Moral, Alonso, Ezquerra, Zapata, Sánchez, Ortuño, Alvarez, Domínguez: Monoclonal antibodies specific for porcine monocytes/macrophages: macrophage heterogeneity in the pig evidenced by the expression of surface antigens. in Tissue antigens 1997 (PubMed)
    Show all 4 Pubmed References

  8. Mouse (Murine) Monoclonal SIGLEC1 Primary Antibody für FACS - ABIN2478775 : Schmied, Vetter, Nussberger, Siegenthaler: Production and characterisation of antisera to 18-hydroxy-11-deoxycorticosterone. in Steroids 1976 (PubMed)
    Show all 3 Pubmed References

  9. Mouse (Murine) Monoclonal SIGLEC1 Primary Antibody für FACS, IF - ABIN2478778 : Alcamo, Hacohen, Schulte, Rennert, Hynes, Baltimore: Requirement for the NF-kappaB family member RelA in the development of secondary lymphoid organs. in The Journal of experimental medicine 2002 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen SIGLEC1 Interaktionspartner

Mouse (Murine) Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1) Interaktionspartner

  1. CD169(+) macrophages are important contributors to the IFN-I response and thereby influence antiviral activity, CD8 (zeige CD8A Antikörper)(+) T-cell exhaustion and immunopathology.

  2. Although CD169 participates in the immune response to tumour antigen and appears to be a positive prognostic marker for human cancers, its role in modulating melanoma growth and metastasis is less clear.

  3. Inhibition of Siglec-1 can prevent atherosclerotic lesion formation by suppress monocytes-endothelial cells adhesion and macrophages accumulation.

  4. Data show that knockdown of sialic acid binding Ig-like lectin 1 (siglec-1) in RAW 264.7 macrophage resulted in inhibiting the production of transforming growth factor beta 1 (TGF-beta1 (zeige TGFB1 Antikörper)) production.

  5. Viral infection significantly upregulated Siglec1 expression in mouse macrophages in an IFN/JAK (zeige JAK3 Antikörper)/STAT1 (zeige STAT1 Antikörper) pathway-dependent manner.

  6. Siglec-1 is a key receptor for macrophage/lymphocyte trans-infection of surface-bound virions, and the N-acyl side chain of sialic acid is a critical determinant for the Siglec-1/MLV interaction.

  7. Robust infection in lymph nodes and spleen requires CD169, suggesting that a combination of fluid-based movement followed by CD169-dependent trans-infection can contribute to viral spread.

  8. CD169(+) monocytes and macrophages have a critical role in preventing excessive inflammation in renal ischemia-reperfusion injury by downregulating intercellular adhesion molecule-1 (zeige ICAM1 Antikörper) expression on vascular endothelial cells.

  9. results identify CD169(+) macrophages as promoters of high-affinity humoral immune responses and emphasize the value of CD169 as target for Ag delivery to improve vaccine responses

  10. Sialoadhesin is critical for macrophages to phagocytose and clear the sialylated pathogen group B Streptococcus.

Human Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1) Interaktionspartner

  1. CD169 expression in regional LNs was not associated with PSA-relapse.

  2. These results highlight the importance of sialic acids on the V1V2 region in binding to sialic acid-binding immunoglobulin-like lectin.

  3. High expression of SIGLEC1 in pregnant women with autoantibodies against Ro/SS-A (zeige TRIM21 Antikörper) indicates an enhanced risk for autoimmune congenital heart block development.

  4. These data demonstrate a prominent role for Siglec-1 in the internalization of HIV-1 to the virus-containing compartment in infected monocyte-derived macrophages

  5. These findings suggest that CD169+ macrophages in RLNs might be a useful marker for assessing clinical stage, including LN states, in patients with breast cancer.

  6. CD169 might act as a co-stimulatory molecule for cytotoxic T-cell activation, and could define a population of tumour-infiltrating macrophages with potential anti-tumour properties in human hepatocellular carcinoma tissues.

  7. In colorectal tumor, malignant melanoma, and endometrial tumor, it was shown that a high density of CD169-positive macrophages in the lymph node sinus was a predictive factor for better clinical prognosis.

  8. Siglec-1 and Siglec-2 (zeige CD22 Antikörper) are potential biomarkers in autoimmune disease. (Review)

  9. Siglec-1 on myeloid cells could fuel novel CD4 (zeige CD4 Antikörper)(+) T-cell infections and contribute to HIV-1 dissemination in vivo.

  10. evidence identifying sialyllactose-containing gangliosides in the viral membrane and the cellular lectin Siglec-1 as critical determinants for HIV-1 capture and storage by mature DCs and for DC-mediated trans-infection of T cells

Pig (Porcine) Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1) Interaktionspartner

  1. the transcription initiation site for sialoadhesin (Siglec-1), which is a porcine alveolar macrophage-specific gene, was determined by 5' rapid amplification of cDNA end.

  2. Fusion protein of sialoadhesin and domains 5-9 of CD163 (zeige CD163 Antikörper) receptors blocked the respiratory syndrome virus infection.

  3. European genotype porcine reproductive and respiratory syndrome virus inhibits porcine alveolar macrophages phagocytosis in vitro, through the interaction with its internalization receptor sialoadhesin.

  4. After infection, PRRSV viremia in SIGLEC1(-/-) pigs followed the same course as in SIGLEC1(-/+) and SIGLEC1(+/+) littermates. The absence of SIGLEC1 had no effect on other aspects of PRRSV infection, including disease course and histopathology.

  5. Endodomain-deletion mutants of sialoadhesin promoted porcine reproductive and respiratory syndrome virus infection less efficiently.

  6. ). These results provided fundamental evidence for CD163 (zeige CD163 Antikörper) and SN as two functional candidate genes affecting immunity in pigs.

  7. effect of antibody binding to pSn on macrophage viability, phagocytosis of microspheres, uptake and processing of soluble antigens, reactive oxygen/nitrogen species production, MHC I and MHC II cell surface expression and cytokine production

  8. Porcine sialoadhesin (CD169/Siglec-1) is an endocytic receptor that allows targeted delivery of toxins and antigens to macrophages.

  9. Sialoadhesin is confirmed as a PRRSV (porcine reproductive and respiratory syndrome virus)internalization receptor and is shown to interact with CD163 (zeige CD163 Antikörper) in PRRSV entry.

  10. Clear changes in the quantity of sialoadhesin(+) and CD163 (zeige CD163 Antikörper)(+) macrophages in the placentas and organs of embryos/fetuses during gestation.

SIGLEC1 Antigen-Profil

Protein Überblick

This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound\; however, the full-length nature of this variant has not been determined.

Genbezeichner und Symbole assoziert mit SIGLEC1

  • sialic acid binding Ig like lectin 1 (SIGLEC1) Antikörper
  • sialic acid binding Ig-like lectin 1, sialoadhesin (Siglec1) Antikörper
  • sialic acid binding Ig like lectin 1 (Siglec1) Antikörper
  • CD169 Antikörper
  • dJ1009E24.1 Antikörper
  • p210 Antikörper
  • pSn Antikörper
  • SA Antikörper
  • SIGLEC-1 Antikörper
  • SIGLEC1 Antikörper
  • SN Antikörper

Bezeichner auf Proteinebene für SIGLEC1

sialoadhesin , SER , sheep erythrocyte receptor , sialic acid-binding Ig-like lectin 1 , sialic acid-binding immunoglobulin-like lectin 1 , Sialic acid-binding Ig-like lectin 1

GENE ID SPEZIES
469866 Pan troglodytes
100345836 Oryctolagus cuniculus
20612 Mus musculus
6614 Homo sapiens
311426 Rattus norvegicus
539759 Bos taurus
397623 Sus scrofa
Ausgewählte Anbieter für anti-SIGLEC1 (SIGLEC1) Antikörper
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