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anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) Antikörper

The protein encoded by NCF4 is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. Zusätzlich bieten wir Ihnen Neutrophil Cytosolic Factor 4, 40kDa Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
NCF4 17972 P97369
NCF4 500904  
NCF4 4689 Q15080
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Top anti-Neutrophil Cytosolic Factor 4, 40kDa Antikörper auf antikoerper-online.de

Showing 10 out of 118 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-NCF4 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Ziege Unkonjugiert ELISA, IHC, WB ABIN190755 (0.5µg/ml) staining of Daudi cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
341,55 €
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of NCF4 antibody (C-term) (ABIN391905) in K562 cell line lysates (35 µg/lane). NCF4 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lymphoma reacted with NCF4 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Hund Ziege Unkonjugiert EIA, IHC (p), WB 0.1 mg Anmelden zum Anzeigen 8 bis 10 Tage
357,50 €
Details
Human Maus Unkonjugiert ELISA Detection limit for recombinant GST tagged NCF4 is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Details
Human Kaninchen Unkonjugiert WB <b>WB Suggested Anti-NCF4 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Human Muscle WB Suggested Anti-NCF4 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: Human Muscle 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert IHC (p) 0.1 mg Anmelden zum Anzeigen 8 bis 10 Tage
385,00 €
Details
Human Kaninchen Unkonjugiert ELISA, IHC Immunohistochemistry analysis of paraffin-embedded human ovary, using p40 phox (Phospho-Thr154) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
288,10 €
Details
Human Kaninchen Unkonjugiert ELISA, IHC Immunohistochemistry analysis of paraffin-embedded human ovary tissue, using p40 phox (Ab-154) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
288,10 €
Details

NCF4 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Mouse (Murine) , , , ,

Rat (Rattus) , , , ,

Human , , , ,
, ,

Am meisten referenzierte anti-Neutrophil Cytosolic Factor 4, 40kDa Antikörper

  1. Human Monoclonal NCF4 Primary Antibody für ELISA - ABIN393677 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Zeige alle 5 Referenzen für ABIN393677

  2. Human Polyclonal NCF4 Primary Antibody für FACS, IHC (p) - ABIN391905 : Glas, Seiderer, Pasciuto, Tillack, Diegelmann, Pfennig, Konrad, Schmechel, Wetzke, Török, Stallhofer, Jürgens, Griga, Klein, Epplen, Schiemann, Mussack, Lohse, Göke, Ochsenkühn, Folwaczny, Müller-Myhsok, Brand: rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population. in The American journal of gastroenterology 2009 (PubMed)
    Zeige alle 2 Referenzen für ABIN391905

  3. Cow (Bovine) Polyclonal NCF4 Primary Antibody für WB - ABIN2782428 : Chen, He, Minshall, Dinauer, Ye: Characterization of a mutation in the Phox homology domain of the NADPH oxidase component p40phox identifies a mechanism for negative regulation of superoxide production. in The Journal of biological chemistry 2007 (PubMed)

  4. Dog (Canine) Polyclonal NCF4 Primary Antibody für EIA, IHC (p) - ABIN374770 : Rioux, Xavier, Taylor, Silverberg, Goyette, Huett, Green, Kuballa, Barmada, Datta, Shugart, Griffiths, Targan, Ippoliti, Bernard, Mei, Nicolae, Regueiro, Schumm, Steinhart, Rotter, Duerr, Cho, Daly et al.: Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. ... in Nature genetics 2007 (PubMed)

Weitere Antikörper gegen Neutrophil Cytosolic Factor 4, 40kDa Interaktionspartner

Mouse (Murine) Neutrophil Cytosolic Factor 4, 40kDa (NCF4) Interaktionspartner

  1. p40phox deficiency leads to upregulation of chemokine receptor 1 (zeige CMKLR1 Antikörper) and downregulation of fucosyltransferases and sialyltransferases involved in glycan modifications during experimental intestinal inflammation.

  2. cooperation of p40(phox) with p47(phox) for Nox2 (zeige CYBB Antikörper)-based NADPH oxidase (zeige NOX1 Antikörper) activation during Fcgamma receptor (FcgammaR)-mediated phagocytosis

  3. The defect in Reactive Oxygen Species production and killing of s aureus by p40(phox-/-) neutrophils defines p40(phox) as an essential component in bacterial killing.

  4. p40 (zeige LANCL1 Antikörper)(phoxR58A/R58A) embryos do not develop normally but p40 (zeige LANCL1 Antikörper)(phoxR58A/-) mice are viable and neutrophils from these animals exhibit significantly reduced oxidase responses compared to those from their p40(phox+/-) siblings.

  5. Class III PI3K Vps34 (zeige PIK3C3 Antikörper) is responsible for the synthesis of PtdIns(3)P on phagosomes containing either S aureus or E coli. PtdIns(3)P binding to p40(phox) is important for CD18 (zeige ITGB2 Antikörper)-dependent activation oxidase activation in response to S aureus and E coli

  6. p40(phox) is prephosphorylated in resting endothelial cells and can compensate p47(phox) in keeping basal ROS (zeige ROS1 Antikörper) production.

Human Neutrophil Cytosolic Factor 4, 40kDa (NCF4) Interaktionspartner

  1. NCF4 may induce ex- pression of NADPH oxidase (zeige NOX1 Antikörper) enzymes, such as p67phox (zeige NCF2 Antikörper), p47phox (zeige NCF1 Antikörper), p22phox (zeige CYBA Antikörper) and NOX2 (zeige CYBB Antikörper), which lead to increased ROS (zeige ROS1 Antikörper) levels.

  2. Germline variation in NCF4, an innate immunity gene, is associated with an increased risk of colorectal cancer.

  3. The contribution of the functionally relevant NADPH (zeige NQO1 Antikörper) polymorphisms rs1883112 and rs4673 to anthracycline-related heart lesions provides a plausible explanation for their modulation of cardiotoxicity.

  4. Constitutive and inducible intracellular production of reactive oxygen species (ROS (zeige ROS1 Antikörper)) is higher in B cells expressing functional p40phox, supporting a direct role for p40phox in regulating B cell intracellular ROS (zeige ROS1 Antikörper) generation.

  5. Genome-wide association studies-reported associations between the NELL1, NCF4, and FAM92B genes and susceptibility to Crohn's disease could not be replicated in Canadian children and young adults.

  6. Younger age at diagnosis, complicated disease behavior, and ileal disease location are risk factors for perianal CD. First report of an association of the NCF4 gene with perianal disease.

  7. cooperation of p40(phox) with p47(phox) for Nox2 (zeige CYBB Antikörper)-based NADPH oxidase (zeige NOX1 Antikörper) activation during Fcgamma receptor (FcgammaR)-mediated phagocytosis

  8. Results demonstrate that PBEF (zeige NAMPT Antikörper) can prime for PMN (zeige TBCE Antikörper) respiratory burst activity by promoting p40 (zeige IL9 Antikörper) and p47 (zeige ING1 Antikörper) translocation to the membrane.

  9. cytosolic localisation depends on direct interaction with F-actin

  10. All mutations and some polymorphisms identified in the NCF4 gene in the autosomal forms of chronic granulomatous disease are listed. Review.

Neutrophil Cytosolic Factor 4, 40kDa (NCF4) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Genbezeichner und Symbole assoziert mit NCF4

  • p40phox protein (p40phox) Antikörper
  • neutrophil cytosolic factor 4 (LOC100136241) Antikörper
  • neutrophil cytosolic factor 4 (Ncf4) Antikörper
  • neutrophil cytosolic factor 4, 40kDa (NCF4) Antikörper
  • AI451400 Antikörper
  • NCF Antikörper
  • P40PHOX Antikörper
  • SH3PXD4 Antikörper

Bezeichner auf Proteinebene für NCF4

p40phox protein , neutrophil cytosolic factor 4 , NADPH oxidase cytosolic protein p40phox , NCF-4 , neutrophil NADPH oxidase factor 4 , neutrophil cytosol factor 4 , p40-phox , SH3 and PX domain-containing protein 4

GENE ID SPEZIES
445891 Takifugu rubripes
100136241 Oncorhynchus mykiss
17972 Mus musculus
500904 Rattus norvegicus
4689 Homo sapiens
481277 Canis lupus familiaris
507859 Bos taurus
100009359 Oryctolagus cuniculus
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