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anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) Antikörper

MAPK8IP1 encodes a regulator of the pancreatic beta-cell function. Zusätzlich bieten wir Ihnen MAPK8IP1 Proteine (4) und MAPK8IP1 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MAPK8IP1 19099 Q9WVI9
MAPK8IP1 116457 Q9R237
MAPK8IP1 9479 Q9UQF2
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Top anti-MAPK8IP1 Antikörper auf antikoerper-online.de

Showing 10 out of 67 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert FACS, IF, IHC (p), WB Western blot analysis of JIP1 Antibody (C-term) (ABIN652961) in MCF-7 cell line lysates (35 µg/lane). JIP1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with JIP1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert IF, ELISA, WB Western blot analysis of extracts from COLO205 cells treated with Serum 20% 15', using JIP1 (Phospho-Thr103) Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of NIH-3T3 cells, using JIP1 (Phospho-Thr103) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA, WB Western blot analysis of extracts from COLO205 cells, treated with Serum 20% 15', using JIP1 (Ab-103) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using JIP1 (Ab-103) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Maus Maus Unkonjugiert FM, WB Western blot analysis of JIP-1 on a mouse cerebellum lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti- JIP-1 antibody. 50 μg Anmelden zum Anzeigen 2 bis 4 Tage
195,64 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of JIP-1 in Jurkat cell lysate (Lane 1) mouse intestine (Lane 2) and rat kidney (Lane 3) tissue lysates. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
337,56 €
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB Western Blot (WB) analysis of specific cells using JIP-1 Polyclonal Antibody. 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details
Maus Kaninchen Unkonjugiert WB 0.1 mg Anmelden zum Anzeigen 8 bis 10 Tage
357,50 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB WB Image Sample(30 ug whole cell lysate) A:Hep G2 , 7.5% SDS PAGE antibody diluted at 1:1000 IHC-P Image JIP1 antibody detects JIP1 protein at cytoplasm on mouse brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse brain. JIP1 antibody , diluted at 1:500. 100 μL Anmelden zum Anzeigen 5 bis 7 Tage
357,24 €
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA, WB 100 μg Anmelden zum Anzeigen 15 bis 21 Tage
419,39 €
Details

MAPK8IP1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-MAPK8IP1 Antikörper

  1. Mouse (Murine) Monoclonal MAPK8IP1 Primary Antibody für FM, WB - ABIN968696 : Bonny, Nicod, Waeber: IB1, a JIP-1-related nuclear protein present in insulin-secreting cells. in The Journal of biological chemistry 1998 (PubMed)
    Zeige alle 3 Referenzen für ABIN968696

  2. Human Polyclonal MAPK8IP1 Primary Antibody für FACS, IF - ABIN652961 : Mooser, Maillard, Bonny, Steinmann, Shaw, Yarnall, Burns, Schorderet, Nicod, Waeber: Genomic organization, fine-mapping, and expression of the human islet-brain 1 (IB1)/c-Jun-amino-terminal kinase interacting protein-1 (JIP-1) gene. in Genomics 1999 (PubMed)

Weitere Antikörper gegen MAPK8IP1 Interaktionspartner

Mouse (Murine) Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) Interaktionspartner

  1. It mediates Alzheimer-disease like pathologies in AICD-Tg mice and that JNK (zeige MAPK8 Antikörper) signaling may contribute to amyloid-independent mechanisms of AD pathogenesis.

  2. Enhanced fast-velocity and efficient high-frequency APP (zeige APP Antikörper) anterograde transport observed in neurons are mediated by novel roles of JIP1b.

  3. a simple yet modular mechanism for JIP1 scaffold assembly in mammals

  4. There is a collaborative relationship between JIP1 and AKT (zeige AKT1 Antikörper) that is required for axon growth and can be regulated by changes in neuronal activity.

  5. identify plenty of SH3 (POSH (zeige SH3RF1 Antikörper)) and JNK-interacting protein 1 (JIP-1) as a multiprotein scaffold network for TCR-mediated JNK1 (zeige MAPK8 Antikörper) activation in CD8 (zeige CD8A Antikörper)(+) T cells.

  6. The phosphorylation of S421 of JIP1 serves as a molecular switch to regulate the direction of APP (zeige APP Antikörper) transport in neurons.

  7. Lysine 63-linked ubiquitination modulates mixed lineage kinase-3 (zeige MAP3K11 Antikörper) interaction with JIP1 scaffold protein (zeige HOMER1 Antikörper) in cytokine-induced pancreatic beta cell death

  8. JIP1 forms a trimetric complex with RBP-Jk (zeige RBPJ Antikörper) and Notch1 (zeige NOTCH1 Antikörper)-IC, prevents physical association between Notch1 (zeige NOTCH1 Antikörper)-IC and RBP-Jk (zeige RBPJ Antikörper), sequesters RBP-JK (zeige RBPJ Antikörper) in the cytoplasm, and suppresses the Notch1 (zeige NOTCH1 Antikörper) signaling pathway.

  9. Data suggest that JIP1-mediated JNK (zeige MAPK8 Antikörper) activation plays a critical role in metabolic stress regulation of the JNK (zeige MAPK8 Antikörper) signaling pathway.

  10. JIP1b can directly modulate APP (zeige APP Antikörper) metabolism by interacting with the APP (zeige APP Antikörper) cytoplasmic domain, independent of its regulation of the JNK (zeige MAPK8 Antikörper) signaling cascade.

Human Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) Interaktionspartner

  1. analysis of the role of JIP1 in APP (zeige APP Antikörper) transport; knockdown of JIP1 did not affect either amyloid precursor protein (zeige APP Antikörper) transport or amyloid-beta peptide production

  2. Data show that small GTPase (zeige RACGAP1 Antikörper) RALA (zeige rala Antikörper) regulates formation of a JIP1 (C-Jun (zeige JUN Antikörper)-amino-terminal-interacting protein 1) scaffold complex to propagate JNK (zeige MAPK8 Antikörper) signaling toward FOXO4 (zeige FOXO4 Antikörper) (forkhead box O (zeige FOXO Antikörper) transcription factor) in response to reactive oxygen species (ROS (zeige ROS1 Antikörper)).

  3. In resected pancreatic cancer, carriers of a minor allele for rs3824872 (MAPK8IP1) were associated with a survival advantage compared with noncarriers with an additional 2-year survival if both minor alleles were present.

  4. Lysine 63-linked ubiquitination modulates mixed lineage kinase-3 (zeige MAP3K11 Antikörper) interaction with JIP1 scaffold protein (zeige HOMER1 Antikörper) in cytokine-induced pancreatic beta cell death

  5. Data suggest that caspase 3 (zeige CASP3 Antikörper)-mediated cleavage of JIP1 scaffold proteins may represent an important mechanism for modulation of JNK (zeige MAPK8 Antikörper) signalling during apoptotic cell death.

  6. Data show that mechanical stress of urothelial cells activates in vivo JNK (zeige MAPK8 Antikörper), as a consequence of a regulated expression of IB1/JIP-1, and that urothelial connexin 26 (zeige GJB2 Antikörper) may be directly regulated by the AP-1 (zeige FOSB Antikörper) complex.

  7. results suggest that JIP (zeige SMAD4 Antikörper)-1b may function as a protein linking the kinesin-I motor protein to the cargo receptor, APP (zeige APP Antikörper), and that the JNK (zeige MAPK8 Antikörper) signaling pathway may regulate the phosphorylation of this cargo protein through the JIP (zeige SMAD4 Antikörper)-1b scaffold

  8. JIP1 may act as an Akt1 (zeige AKT1 Antikörper) scaffold, which regulates the enzymatic activity of Akt1 (zeige AKT1 Antikörper) and can exert signaling effects independent of JNK (zeige MAPK8 Antikörper) activity

  9. JIP-1 protein may regulate kinesin-I-dependent neuronal AbetaPP transport, which controls AbetaPP processing

  10. JIP-1 only facilitated (but is not required for) phosphorylation of Amyloid beta protein precursor but not of the two other family members APLP1 (amyloid precursor-like protein 1 (zeige APLP1 Antikörper)) and APLP2 (zeige APLP2 Antikörper)

MAPK8IP1 Antigen-Profil

Protein Überblick

This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes.

Genbezeichner und Symbole assoziert mit MAPK8IP1

  • mitogen-activated protein kinase 8 interacting protein 1 (MAPK8IP1) Antikörper
  • mitogen-activated protein kinase 8 interacting protein 1 (LOC100344706) Antikörper
  • mitogen-activated protein kinase 8 interacting protein 1 (Mapk8ip1) Antikörper
  • IB1 Antikörper
  • Jip-1 Antikörper
  • JIP1 Antikörper
  • Mapk8ip Antikörper
  • mjip-2a Antikörper
  • PRKM8IP Antikörper
  • Skip Antikörper

Bezeichner auf Proteinebene für MAPK8IP1

mitogen-activated protein kinase 8 interacting protein 1 , c-Jun-amino-terminal kinase-interacting protein 1-like , C-Jun-amino-terminal kinase-interacting protein 1 , IB-1 , JNK MAP kinase scaffold protein 1 , JNK-interacting protein 1 , islet-brain-1 , mitogen activated protein kinase 8 interacting protein 1 , mitogen-activated protein kinase 8-interacting protein 1 , protein kinase, mitogen-activated 8 interacting protein , JIP-1-related protein , JRP , mitogen activated protein kinase 8 interacting protein , PRKM8 interacting protein , islet-brain 1 , islet brain 1

GENE ID SPEZIES
423202 Gallus gallus
100344706 Oryctolagus cuniculus
100473891 Ailuropoda melanoleuca
19099 Mus musculus
116457 Rattus norvegicus
9479 Homo sapiens
483640 Canis lupus familiaris
524806 Bos taurus
Ausgewählte Anbieter für anti-MAPK8IP1 (MAPK8IP1) Antikörper
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