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anti-K(lysine) Acetyltransferase 2A (KAT2A) Antikörper

KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. Zusätzlich bieten wir Ihnen K(lysine) Acetyltransferase 2A Proteine (12) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
KAT2A 2648 Q92830
KAT2A 14534 Q9JHD2
KAT2A 303539  
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Top anti-K(lysine) Acetyltransferase 2A Antikörper auf antikoerper-online.de

Showing 10 out of 110 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB KAT2A Antibody (C-term) (ABIN657013) western blot analysis in UM cell line lysates (35 µg/lane). This demonstrates the KAT2A antibody detected the KAT2A protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of anti-GCN5 Antibody (N-term)(ABIN387930) in 293 cell line lysates (35 µg/lane). GCN5(arrow) was detected using the purified polyclonal antibody (1:60 dilution). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Maus Unkonjugiert EIA, IF, WB 0.1 mL Anmelden zum Anzeigen 8 bis 10 Tage
341,00 €
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Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 8 bis 10 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of KAT2A / GCN5L2 Antibody (C-term) in UM cell line lysates (35ug/lane). This demonstrates the KAT2A antibody detected the KAT2A protein (arrow). 0.4 mL Anmelden zum Anzeigen 8 bis 10 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert EIA, FACS, WB Flow cytometric analysis of Neuro-2a cells using KAT2A / GCN5L2 Antibody (C-term) Cat.-No AP52039PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis. Western blot analysis of KAT2A / GCN5L2 Antibody (C-term) in mouse Neuro-2a cell line lysates (35ug/lane). 0.4 mL Anmelden zum Anzeigen 8 bis 10 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from mouse brain cells, using GCN5L2 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert FACS, WB hGCN5 Antibody (C-term) (ABIN656132) western blot analysis in mouse Neuro-2a cell line lysates (35 µg/lane). This demonstrates the hGCN5 antibody detected the hGCN5 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
340,48 €
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB Western Blot (WB) analysis of specific cells using GCN5 Polyclonal Antibody. 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details

KAT2A Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Mouse (Murine)
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Rat (Rattus)


Am meisten referenzierte anti-K(lysine) Acetyltransferase 2A Antikörper

  1. Human Polyclonal KAT2A Primary Antibody für EIA, WB - ABIN356619 : Kikuchi, Takami, Nakayama: GCN5: a supervisor in all-inclusive control of vertebrate cell cycle progression through transcription regulation of various cell cycle-related genes. in Gene 2005 (PubMed)
    Zeige alle 4 Referenzen für ABIN356619

  2. Human Polyclonal KAT2A Primary Antibody für EIA, FACS - ABIN952987 : Kelly, Lerin, Haas, Gygi, Puigserver: GCN5-mediated transcriptional control of the metabolic coactivator PGC-1beta through lysine acetylation. in The Journal of biological chemistry 2009 (PubMed)
    Zeige alle 3 Referenzen für ABIN952987

  3. Human Polyclonal KAT2A Primary Antibody für EIA, WB - ABIN952986 : Mao, Gluck, Li, Maine, Li, Zaidi, Repaka, Mayo, Burstein: GCN5 is a required cofactor for a ubiquitin ligase that targets NF-kappaB/RelA. in Genes & development 2009 (PubMed)
    Zeige alle 3 Referenzen für ABIN952986

  4. Human Monoclonal KAT2A Primary Antibody für EIA, IF - ABIN487348 : Wiper-Bergeron, Salem, Tomlinson, Wu, Haché: Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBPbeta by GCN5. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)
    Zeige alle 3 Referenzen für ABIN487348

  5. Human Polyclonal KAT2A Primary Antibody für WB - ABIN387930 : Oishi, Kitagawa, Wada, Takezawa, Tora, Kouzu-Fujita, Takada, Yano, Yanagisawa, Kato: An hGCN5/TRRAP histone acetyltransferase complex co-activates BRCA1 transactivation function through histone modification. in The Journal of biological chemistry 2006 (PubMed)
    Zeige alle 2 Referenzen für ABIN387930

  6. Human Polyclonal KAT2A Primary Antibody für ELISA, WB - ABIN1534045 : Yang, Ogryzko, Nishikawa, Howard, Nakatani: A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. in Nature 1996 (PubMed)

Weitere Antikörper gegen K(lysine) Acetyltransferase 2A Interaktionspartner

Human K(lysine) Acetyltransferase 2A (KAT2A) Interaktionspartner

  1. Data suggest that expression of GCN5 (histone acetyltransferase GCN5) is induced in skeletal muscle during a 48-hour fast; in contrast, expression of SIRT1 (sirtuin 1 (zeige SIRT1 Antikörper)) remains unchanged.

  2. Orc5 (zeige ORC5 Antikörper) associates with the H3 histone (zeige HIST1H3B Antikörper) acetyl transferase (zeige HAT1 Antikörper) GCN5 (also known as KAT2A), and this association enhances the chromatin-opening function of Orc5 (zeige ORC5 Antikörper).

  3. Methionine was the only essential amino acid that rapidly induced PGC-1alpha acetylation through activating the GCN5 acetyltransferase.

  4. these results may point to the GCN5-NF-kappaB (zeige NFKB1 Antikörper) pathway as a novel potential molecular target for stem cell mediated regenerative medicine and the treatment of metabolic bone diseases such as osteoporosis.

  5. Acetyltransferase p300 (zeige EP300 Antikörper) collaborates with chromodomain helicase DNA-binding protein 4 (CHD4 (zeige CHD4 Antikörper)) to facilitate DNA double-strand break repair

  6. Suggest lysine acetyltransfer as a potential regulator of platelet actin dynamics, and potential roles for lysine acetylation in the molecular coordination of platelet activation and function.

  7. Data uncover GCN5 as a negative regulator of C/EBPalpha (zeige CEBPA Antikörper) and demonstrate the importance of C/EBPalpha (zeige CEBPA Antikörper) acetylation in myeloid differentiation.

  8. GCN5 Potentiates Glioma Proliferation and Invasion via STAT3 (zeige STAT3 Antikörper) and AKT (zeige AKT1 Antikörper) Signaling Pathways

  9. results thus demonstrate that the catalytic activity of GCN5 is stimulated by subunits of the ADA2a (zeige TADA2A Antikörper)- or ADA2b (zeige TADA2B Antikörper)-containing HAT (zeige MGEA5 Antikörper) modules and is further increased by incorporation of the distinct HAT (zeige MGEA5 Antikörper) modules in the ATAC (zeige XCL1 Antikörper) or SAGA holo-complexes

  10. GCN5 plays a positive role in human colon cancer development, and its suppression holds a great therapeutic potential in antitumor therapy

Mouse (Murine) K(lysine) Acetyltransferase 2A (KAT2A) Interaktionspartner

  1. Methionine was the only essential amino acid that rapidly induced PGC-1alpha acetylation through activating the GCN5 acetyltransferase.

  2. these results may point to the GCN5-NF-kappaB (zeige NFKB1 Antikörper) pathway as a novel potential molecular target for stem cell mediated regenerative medicine and the treatment of metabolic bone diseases such as osteoporosis.

  3. In addition to reducing atrogene expression, surprisingly inhibiting NF-kappaB (zeige NFKB1 Antikörper) with IkappaBalpha (zeige NFKBIA Antikörper)-SR or by GCN5 knockdown in these muscles also enhanced AKT (zeige AKT1 Antikörper) and mechanistic target of rapamycin (mTOR (zeige FRAP1 Antikörper)) activities, which also contributed to the reduction in atrophy.

  4. Gcn5 and PCAF (zeige KAT2B Antikörper) repress IFN-beta (zeige IFNB1 Antikörper) production in an enzymatic activity-independent and non-transcriptional manner: by inhibiting the innate immune signaling kinase TBK1 (zeige TBK1 Antikörper) in the cytoplasm.

  5. GCN5 and HDAC1 (zeige HDAC1 Antikörper) are the crucial enzymes that regulating epigenetic reprogramming; we observed dynamic changes in the expression levels of GCN5 and HDAC1 (zeige HDAC1 Antikörper) during embryo development

  6. In conclusion, these data establish Kat2a as a novel and essential regulator of hippocampal memory consolidation.

  7. Study reveals that Gcn5/PCAF (zeige KAT2B Antikörper) facilitate adipogenesis through regulation of PPARgamma (zeige PPARG Antikörper) expression and regulate brown adipogenesis by influencing Prdm16 (zeige PRDM16 Antikörper) expression.

  8. Sirt6 interacts with and modifies GCN5, enhancing GCN5's activity.

  9. Data support a model in which p23 and GCN5 regulate diverse multistep pathways by controlling the longevity of protein-DNA complexes.

  10. Data have defined an important role for GCN5 in NSC and provided evidence that GCN5 is an important Myc (zeige MYC Antikörper) transcriptional cofactor in vivo.

K(lysine) Acetyltransferase 2A (KAT2A) Antigen-Profil

Protein Überblick

KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009

Genbezeichner und Symbole assoziert mit KAT2A

  • K(lysine) acetyltransferase 2A (KAT2A) Antikörper
  • K(lysine) acetyltransferase 2A (kat2a) Antikörper
  • K(lysine) acetyltransferase 2A (Kat2a) Antikörper
  • 1110051E14Rik Antikörper
  • AW212720 Antikörper
  • Gcn5 Antikörper
  • Gcn5l2 Antikörper
  • hGCN5 Antikörper
  • KAT2A Antikörper
  • mmGCN5 Antikörper
  • PCAF-b Antikörper

Bezeichner auf Proteinebene für KAT2A

histone acetyltransferase KAT2A , general control of amino acid synthesis 5-like 2 , GCN5 general control of amino-acid synthesis 5-like 2 , general control of amino acid synthesis protein 5-like 2 , K(lysine) acetyltransferase 2A , GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2 , General control of amino acid synthesis, yeast, homolog-like 2 , STAF97 , histone acetyltransferase GCN5 , hsGCN5 , lysine acetyltransferase 2A , GCN5 general control of amino acid synthesis-like 2 , PCAF-B/GCN5 , general control of amino acid synthesis, yeast homolog-like 2 , general control of amino acid synthesis-like 2

GENE ID SPEZIES
552646 Apis mellifera
374232 Gallus gallus
454677 Pan troglodytes
490971 Canis lupus familiaris
100176452 Ciona intestinalis
100597293 Nomascus leucogenys
2648 Homo sapiens
14534 Mus musculus
303539 Rattus norvegicus
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