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APOB product is the main apolipoprotein of chylomicrons and low density lipoproteins. Zusätzlich bieten wir Ihnen APOB Kits (121) und APOB Proteine (19) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 355 products:
Human Monoclonal APOB Primary Antibody für ICC, FACS - ABIN968961
Peterson, Mack, Hall, Alsup, Alexander, Sully, Sawires, Cheung, Otto, Gresham: Apolipoprotein B Is an innate barrier against invasive Staphylococcus aureus infection. in Cell host & microbe 2008
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Guinea Pig Polyclonal APOB Primary Antibody für ID - ABIN2477467
Hazell, Arnold, Flowers, Waeg, Malle, Stocker: Presence of hypochlorite-modified proteins in human atherosclerotic lesions. in The Journal of clinical investigation 1996
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Human Polyclonal APOB Primary Antibody für IHC (p), IP - ABIN267960
Bakillah, Tedla, Ayoub, John, Norin, Hussain, Brown: Plasma Nitration of High-Density and Low-Density Lipoproteins in Chronic Kidney Disease Patients Receiving Kidney Transplants. in Mediators of inflammation 2015
Human Polyclonal APOB Primary Antibody für IP, ELISA - ABIN2477466
Davidson, Appel, Doster, Baker, Brown: Diseases and parasites of red foxes, gray foxes, and coyotes from commercial sources selling to fox-chasing enclosures. in Journal of wildlife diseases 1993
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Human Polyclonal APOB Primary Antibody für ELISA, WB - ABIN449695
Benn, Nordestgaard, Jensen, Tybjaerg-Hansen: Polymorphisms in apolipoprotein B and risk of ischemic stroke. in The Journal of clinical endocrinology and metabolism 2007
Human Polyclonal APOB Primary Antibody für IF (p), IHC (p) - ABIN872950
Choi, de Poot, Lee, Kim, Han, Kim, Finley, Lee: Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation. in Nature communications 2016
Human Monoclonal APOB Primary Antibody für FACS, IF - ABIN965573
Benn: Apolipoprotein B levels, APOB alleles, and risk of ischemic cardiovascular disease in the general population, a review. in Atherosclerosis 2009
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Human Polyclonal APOB Primary Antibody für RID, WB - ABIN152417
Tsai, Hsu, Hsu, Lai, Chen, Shen, Huang, Chen, Lee, Tsai, Hsu, Wu, Huang, Shiao, Hsiao, Tsou: MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis. in The Journal of clinical investigation 2012
Human Monoclonal APOB Primary Antibody für RIA, ELISA - ABIN535615
Lin, Gordon, Wetterau: Microsomal triglyceride transfer protein (MTP) regulation in HepG2 cells: insulin negatively regulates MTP gene expression. in Journal of lipid research 1995
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Association of plasma apoB with IR in obese subjects is dependent on gynoid WAT dysfunction
Serum ApoB was not significantly different between term SGA newborns and control term newborns.
This study showed that the predictive value of apolipoprotein B/A-I ratio for coronary artery calcification may differ according to kidney function.
APOB associated with Familial Hypercholesterolemia and Polygenic Hypercholesterolemia in patients with Acute Coronary Syndrome , age =65 years, and LDL-C levels >/=160 mg/dl.
we identified common intronic SNPs (rs676210 and rs1042034) in the APOB gene and found five SNPs that were collectively associated with hyperlipidemia in the adult Chinese Yugur population. Importantly, we demonstrated that the G allele of rs676210 may confer an increased risk of hyperlipidemia.
APOB missense variants, A224T and V925L, in a black South African woman with marked hypocholesterolemia
male gender, ageing in women and menopause were associated with increased apoB concentrations.
Data provide no evidence supporting an association between the APOB R3527Q variant and type 2 diabetes or glycemia.
Levels of lipoprotein (a) [Lp(a (zeige APOA Antikörper))], a complex between an LDL-like lipid moiety containing one copy of apoB, and apo(a (zeige APOA Antikörper)), a plasminogen (zeige PLG Antikörper)-derived carbohydrate-rich hydrophilic protein, are primarily genetically rIncreasing evidence suggests that age, sex, and hormonal impact may have a modest modulatory influence on Lp(a (zeige APOA Antikörper)) levels. Among clinical conditions, Lp(a (zeige APOA Antikörper)) levels are reported to be affected by kidney and liver diseases.
Data suggest that amphipathic beta-strands in 200 N-terminal residues of beta1 domain of APOB are required for secretion of lipid-rich or lipid-poor particles; residues 300-700 or 1050-1500 of beta1 domain appear to be required for secretion of lipid-rich particles; MTTP (zeige MTTP Antikörper) is required for secretion of intact APOB but not of truncated APOB. (APOB = apolipoprotein B; MTTP (zeige MTTP Antikörper) = microsomal triglyceride transfer protein (zeige MTTP Antikörper))
We carried out our experiment in mice deficient in the low density lipoprotein (LDL) receptor (zeige LDLR Antikörper) and expressing only ApoB100 molecule (ApoB - LDLr (zeige LDLR Antikörper)) where the development of atherosclerosis is known to closely mimic human atherosclerosis
The effect of hypercholesterolemia induced immune response and inflammation on progression of atherosclerosis in ApoB(tm25gy) LDLr (zeige LDLR Antikörper)(tm1Her) mice, expressing only ApoB100 and deficient in the low density lipoprotein receptor (zeige LDLR Antikörper).
ApoB-containing lipoproteins contribute to augmentation of AngII-induced abdominal aortic aneurysms in male mice.
Immunization with human apolipoprotein B100 (ApoB) resulted in four-fold increased accumulation of effector T cells in ApoB-containing matrigel
PCSK9 (zeige PCSK9 Antikörper) markedly increases intestinal triglyceride-rich apoB production through mechanisms mediated in part by transcriptional effects on apoB.
Mice that produce apoB100 in the RPE (zeige RPE Antikörper) and liver secrete lipoproteins into Bruch's membrane, but not to the extent that distinct features of AMD (zeige AMD1 Antikörper) develop
The aim of this study was to characterize the ocular morphology of low-density lipoprotein receptor-deficient apolipoprotein B-100-only mice, with IGF-II overexpression.
Our data establish the role of APOB gene in severe gut (zeige GUSB Antikörper) dysmotility.
Cardiac lipotoxicity may originate from direct inhibition of myocardial ApoB lipoprotein and subsequent decreased lipid export, caused by supraphysiological levels of catecholamines.
ApoB-100 transgenic animals present i) elevated serum and cerebral levels of triglycerides and ApoB-100, ii) increased cerebral tau phosphorylation at phosphosites Ser (zeige SIGLEC1 Antikörper)(199), Ser (zeige SIGLEC1 Antikörper)(199/202), Ser (zeige SIGLEC1 Antikörper)(396) and Ser (zeige SIGLEC1 Antikörper)(404).
Beyond malabsorption of dietary lipids, deleterious effects of apolipoprotein B deficiency on hepatic lipid metabolism, steroid biosynthesis, and cell membrane function can be expected, which may result in unspecific symptoms of reduced fertility, growth, and health.
Cholesterol deficiency results from a 1.3kbp insertion of an endogenous retrovirus (ERV2-1-LTR_BT) into exon 5 of the APOB gene at BTA11:77,959kb. The insertion is flanked by 6bp target site duplications as described for insertions mediated by retroviral integrases.
A transposable element insertion in APOB causes cholesterol deficiency in Holstein cattle
Nonesterified fatty acids significantly inhibit the expression of ApoB100, ApoE (zeige APOE Antikörper), MTP (zeige MTTP Antikörper), and LDLR (zeige LDLR Antikörper), thereby decreasing the synthesis and assembly of VLDL and inducing TG accumulation in bovine hepatocytes.
after calving the apolipoprotein B(100) mRNA synthesis was lower, whereas microsomal triglyceride transfer protein (MTP (zeige MTTP Antikörper)) and apolipoprotein E (zeige APOE Antikörper) messenger RNA abundance were higher in the liver.
found association between genotypes for LDLR (zeige LDLR Antikörper) and APOB polymorphisms and serum lipid levels, but none of them seem to be the causal mutation but probably represent closely linked polymorphisms
This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.
, apolipoprotein B (including Ag(x) antigen)
, apolipoprotein B-100
, apolipoprotein B48
, mutant Apo B 100
, apolipoprotein B PI
, apolipoprotein B-48
, apolipoprotein B