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anti-KREMEN1 (KREMEN1) Antikörper

Bezeichnung:: anti-Kringle Containing Transmembrane Protein 1 Antikörper (KREMEN1)

Auf www.antikoerper-online.de finden Sie aktuell 100 Kringle Containing Transmembrane Protein 1 (KREMEN1) Antikörper von 22 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen KREMEN1 Proteine (11) und KREMEN1 Kits (9) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 129 KREMEN1 Produkte verfügbar.

Synonyme:: AV002070, kremem1, Kremen, KREMEN1, Krm1, si:ct737139.1, si:dkeyp-7c9.1

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	KREMEN1	83999	Q96MU8
	KREMEN1	84035	Q99N43
	KREMEN1	114107	Q924S4
Alle Spezies anzeigen Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-KREMEN1 (KREMEN1) Antikörper

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anti-Human KREMEN1 Antikörper:

anti-Mouse (Murine) KREMEN1 Antikörper:

anti-Rat (Rattus) KREMEN1 Antikörper:

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Verknüpfte Pathways mit anti-KREMEN1 Antikörper

WNT Signalweg

Weitere Produktkategorien zu KREMEN1 Antikörper

Am meisten referenzierte anti-KREMEN1 Antikörper

Human Polyclonal KREMEN1 Primary Antibody für ELISA, WB - ABIN543953 : Nakamura, Aoki, Kitajima, Takahashi, Matsumoto, Nakamura: Molecular cloning and characterization of Kremen, a novel kringle-containing transmembrane protein. in Biochimica et biophysica acta 2001 (PubMed)
Show all 2 Pubmed References
Human Polyclonal KREMEN1 Primary Antibody für IHC (p), ELISA - ABIN542856 : Mao, Wu, Davidson, Marhold, Li, Mechler, Delius, Hoppe, Stannek, Walter, Glinka, Niehrs: Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling. in Nature 2002 (PubMed)
Show all 2 Pubmed References
Mouse (Murine) Polyclonal KREMEN1 Primary Antibody für CyTOF, FACS - ABIN4899514 : Diarra, Stolina, Polzer, Zwerina, Ominsky, Dwyer, Korb, Smolen, Hoffmann, Scheinecker, van der Heide, Landewe, Lacey, Richards, Schett: Dickkopf-1 is a master regulator of joint remodeling. in Nature medicine 2007 (PubMed)
Show all 2 Pubmed References

Weitere Antikörper gegen KREMEN1 Interaktionspartner

Human Kringle Containing Transmembrane Protein 1 (KREMEN1) Interaktionspartner

Dkk4 CRD2 mediates high-affinity binding to both the E1E2 region of low-density lipoprotein receptor-related protein 6 (LRP6 E1E2) and the Kremen1 (Krm1) extracellular domain.
Structure of the dual-mode Wnt regulator Kremen1 and insight into ternary complex formation with LRP6 and DKK1 have been presented.
Ectodermal dysplasia including oligodontia is due to homozygosity for KREMEN1 p.F209S (c.626 T>C).
Kremen1 has a pro-apoptotic activity that is decreased upon Dkk1 binding or by cancer mutations.
Six Dkk-1, three Sost, one Kremen-1 and 10 LRP-5 polymorphisms were significantly associated with radiological progression of rheumatoid arthritis joint destruction.
The mRNA expression levels of DKK-1 binding receptor LRP5/6 and Krm1/2 in SCs from patients with MM were significantly higher than those in myeloma cells and in SCs from healthy donors.
This study demonstrated that a representative tSNP of KREMEN1 might modulate the risk of schizophrenia in the Japanese population.
Kremen may not be essential for Dkk1-mediated Wnt antagonism and Kremen may only play a role when cells express a high level of LRP5/6
Functional characterization of related Kremen proteins in mouse.

Mouse (Murine) Kringle Containing Transmembrane Protein 1 (KREMEN1) Interaktionspartner

Kremen1 is expressed in prosensory cells during cochlear developme
Kremen1 has a pro-apoptotic activity that is decreased upon Dkk1 binding
Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling
Dkk1 and Kremen1 play roles in blastocyst activation and uterine receptivity during the window of implantation.
Kremen may not be essential for Dkk1-mediated Wnt antagonism and Kremen may only play a role when cells express a high level of LRP5/6
This study provides the first genetic evidence for a functional interaction of Kremen proteins with Dkk1 as negative regulators of Wnt/beta-catenin signaling.

Zebrafish Kringle Containing Transmembrane Protein 1 (KREMEN1) Interaktionspartner

Data show that fish lacking Kremen1 protein develop more hair cells per neuromast compared to wild type fish.
Kremen1 modulates Wnt activity by restricting the range of secreted Dkk proteins during collective cell migration in the posterior lateral line primordium

KREMEN1 Antigen-Profil

Beschreibung des Gens

This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.

Alternative names and synonyms associated with KREMEN1

kringle containing transmembrane protein 1 (KREMEN1) Antikörper
kringle containing transmembrane protein 1 (kremen1) Antikörper
kringle containing transmembrane protein 1 (Kremen1) Antikörper
kringle containing transmembrane protein 1 S homeolog (kremen1.S) Antikörper

AV002070 Antikörper
kremem1 Antikörper
Kremen Antikörper
KREMEN1 Antikörper
Krm1 Antikörper
si:ct737139.1 Antikörper
si:dkeyp-7c9.1 Antikörper

Bezeichner auf Proteinebene für KREMEN1

kringle containing transmembrane protein 1 , kringle-containing transmembrane protein 1 , kremen 1 , kremen protein 1-like , dickkopf receptor , kremen protein 1 , kringle domain-containing transmembrane protein 1 , kringle-coding gene marking the eye and the nose , kringle-containing protein marking the eye and the nose , krm1

GENE ID	SPEZIES
416920	Gallus gallus
486340	Canis lupus familiaris
524357	Bos taurus
748246	Pan troglodytes
100064476	Equus caballus
100144698	Xenopus (Silurana) tropicalis
100407744	Callithrix jacchus
100438112	Pongo abelii
100470669	Ailuropoda melanoleuca
100543996	Meleagris gallopavo
100595234	Nomascus leucogenys
83999	Homo sapiens
84035	Mus musculus
398249	Xenopus laevis
114107	Rattus norvegicus
100141352	Danio rerio

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