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Human Polyclonal Aurora Kinase B Primary Antibody für ICC, IF - ABIN151760
Adams, Eckley, Vagnarelli, Wheatley, Gerloff, Mackay, Svingen, Kaufmann, Earnshaw: Human INCENP colocalizes with the Aurora-B/AIRK2 kinase on chromosomes and is overexpressed in tumour cells. in Chromosoma 2001
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Human Polyclonal Aurora Kinase B Primary Antibody für ICC, IF - ABIN152999
Qi, Tang, Yu: Phosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is required for the kinetochore localization of Plk1. in Molecular biology of the cell 2006
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Human Monoclonal Aurora Kinase B Primary Antibody für ELISA, WB - ABIN965626
Song, So, Cheng, Tang, Croft: Sustained survivin expression from OX40 costimulatory signals drives T cell clonal expansion. in Immunity 2005
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Human Monoclonal Aurora Kinase B Primary Antibody für ELISA, WB - ABIN1724660
Kapoor, Lavoie, Frappier: EBP2 plays a key role in Epstein-Barr virus mitotic segregation and is regulated by aurora family kinases. in Molecular and cellular biology 2005
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Human Polyclonal Aurora Kinase B Primary Antibody für ELISA, WB - ABIN129612
Mackay, Makise, Ullman: Defects in nuclear pore assembly lead to activation of an Aurora B-mediated abscission checkpoint. in The Journal of cell biology 2010
Human Polyclonal Aurora Kinase B Primary Antibody für EIA, WB - ABIN117978
Honda, Asato, Tanaka, Endo, Nishimura, Ito: Vidian nerve schwannoma with middle cranial fossa extension resected via a maxillary swing approach. in Head & neck 2008
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Human Polyclonal Aurora Kinase B Primary Antibody für ICC, IF - ABIN408113
Togashi, Shirakawa, Orime, Kaji, Sakamoto, Tajima, Inoue, Nakamura, Tochino, Goshima, Shimomura, Terauchi: β-Cell proliferation after a partial pancreatectomy is independent of IRS-2 in mice. in Endocrinology 2014
Chimpanzee Polyclonal Aurora Kinase B Primary Antibody für ELISA, WB - ABIN2477557
Klever, Grond-Ginsbach, Hager, Schroeder-Kurth: Chorionic villus metaphase chromosomes and interphase nuclei analysed by chromosomal in situ suppression (CISS) hybridization. in Prenatal diagnosis 1992
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Human Polyclonal Aurora Kinase B Primary Antibody für WB - ABIN2441645
Bailey, Fields, Cheng, Lee, Wagenaar, Lagrois, Schmidt, Xia, Ma: WD repeat-containing protein 5 (WDR5) localizes to the midbody and regulates abscission. in The Journal of biological chemistry 2015
Results show the overexpression Aurkb decreased glycolytic activities and suggest that AURKB is involved in asthenozoospermia.
Identification and characterization of AURKB and AURKC (zeige AURKC Antikörper) variants associated with maternal aneuploidy has been reported.
SIX3 is a novel negative transcriptional regulator and acts as a tumor suppressor that directly represses the transcription of AURKA (zeige AURKA Antikörper) and AURKB in astrocytoma.
Our findings suggested that AURKA (zeige AURKA Antikörper) (rs911160) and AURKB (rs2289590) polymorphisms could affect GC risk. Further validation studies in larger and multi-ethnical populations are needed to elucidate their functional impact on the development of GC
Data show that aurora-B regulates end-on conversion in human cells and indicate a late role for SPAG5 (zeige SPAG5 Antikörper) protein (Astrin (zeige SPAG5 Antikörper))-SKAP (zeige KNSTRN Antikörper) complex in the end-on conversion process.
The results of experiment indicated that specific knockdown of Aurora kinase B led to prostate carcinoma cells apoptosis and inhibited tumor growth.
decrease in Aurora B results in diminished binding of the chromokinesin Kif4A to chromosome arms.
Aurora B kinase interacts with and phosphorylates Sgo1 (zeige SGOL1 Antikörper). Aurora B-mediated phosphorylation of Sgo1 (zeige SGOL1 Antikörper) regulates the distribution of Sgo1 (zeige SGOL1 Antikörper) between centromeres and chromosome arms.
AURKC (zeige AURKC Antikörper) rs758099 TT and (CC + CT) genotypes were positively associated with increased intestinal type gastric cancer (GC)risk, but not with an increased diffuse type GC risk. Based on these results, we can conclude that AURKA (zeige AURKA Antikörper) rs1047972 and AURKC (zeige AURKC Antikörper) rs758099 polymorphisms could affect the risk of GC development.
Aurora-C (zeige AURKC Antikörper) interactions with members of the Chromosome Passenger Complex (CPC), Survivin (zeige BIRC5 Antikörper) and Inner Centromere Protein (INCENP (zeige INCENP Antikörper)) in reference to known Aurora-B interactions to understand the functional significance of Aurora-C (zeige AURKC Antikörper) overexpression in human cancer cells, is reported.
Data show that phosphorylated Ku70 (zeige XRCC6 Antikörper) S155 interacts with the Aurora B kinase and leads to inhibition of its activity.
Loss of AURKB function affects TERF1 (zeige TERF1 Antikörper) telomere binding and results in aberrant telomere structure.
The high sequence similarity among the AURK family members has made discerning the individual kinase functions in meiosis challenging. Technical limitations in specifically targeting AURKB or AURKC (zeige AURKC Antikörper) using small-molecule inhibitors and compensatory abilities in single-knockout animals add to this challenge...proper regulation of AURKA (zeige AURKA Antikörper) expression is crucial for spindle formation in meiosis
Aurkb phosphorylates Oct4 (zeige POU5F1 Antikörper)(S229) during G2/M phase, leading to the dissociation of Oct4 (zeige POU5F1 Antikörper) from chromatin, whereas PP1 (zeige PPP1CC Antikörper) binds Oct4 (zeige POU5F1 Antikörper) and dephosphorylates Oct4 (zeige POU5F1 Antikörper)(S229) during M/G1 transition, which resets Oct4 (zeige POU5F1 Antikörper)-driven transcription for pluripotency and the cell cycle.
Overexpression of Aurora B (zeige AURKC Antikörper) also results in a reduced DNA damage response and decreased levels of the p53 (zeige TP53 Antikörper) target p21(Cip1 (zeige CDKN1A Antikörper)) in vitro and in vivo.
Chromsome stability is on of the tumor-suppressive functions of ARF as well as regulation of Aurora B (zeige AURKC Antikörper) expression in tumors.
Using this mutant we show for the first time that AURKC has functions that do not overlap with AURKB. These functions include regulating localized CPC activity and regulating chromosome alignment and K-MT attachments at metaphase of meiosis I (Met I).
reduced accumulation of Aurora B (zeige AURKC Antikörper) at the inner centromere region in cells lacking Pds5B (zeige PDS5B Antikörper) impairs its error correction function, promoting chromosome mis (zeige AMH Antikörper)-segregation and aneuploidy
Aurora B (zeige AURKC Antikörper) and Ring1B (zeige RNF2 Antikörper) co-occupy active promoters in resting lymphocytes.
FBXL2 (zeige FBXL2 Antikörper) mediates Aurora B (zeige AURKC Antikörper) ubiquitination and degradation within the midbody, which is sufficient to induce mitotic arrest and apoptosis.
Aurora A (zeige AURKA Antikörper) and B kinases directly phosphorylate Lgl to promote its mitotic relocalization.
Regulation of Polo (zeige PLK1 Antikörper) by Aurora B and Map205 is required for cytokinesis.
We propose that mutual inhibitions between Aurora B and Cyclin B regulate the duration of abscission and thereby the number of sister cells in each cyst.
Aurora B kinase activity is not required during contractile ring ingression, providing insight into the mechanism of cytokinesis.
Aurora B interacts with and requires the Cdc37 (zeige CDC37 Antikörper)/Hsp90 (zeige HSP90 Antikörper) complex for its stability.
INCENP (zeige INCENP Antikörper) binds to the cohesion protector protein (zeige PRDX2 Antikörper) MEI-S332, which is also an excellent in vitro substrate for Aurora B kinase.
Alterations in PGRMC1 (zeige PGRMC1 Antikörper) and/or AURKB localization account in part for the increased aneuploidy and low development competence of oocytes from ovaries with reduced antral follicle counts.
AURKB associated with metaphase chromosomes.
Aurora B kinase is essential for furrow induction and maturation in the zebrafish embryo.
Data suggest a model in which microtubules act as scaffolds for the enzymatic activity of Aurora-B.
Data report the crystal structure of Aurora B in complex with the IN-box segment of the inner centromere protein (INCENP (zeige INCENP Antikörper)) activator and with the small molecule inhibitor Hesperadin.
ICIS (zeige MTUS1 Antikörper) and Aurora B coregulate the microtubule depolymerase Kif2a (zeige KIF2A Antikörper).
the Aurora B chromosome passenger protein complex, including INCENP (zeige INCENP Antikörper) and survivin, is regulated during oocyte maturation in Xenopus laevis
This study reveals a new role for Aurora B, which is to prevent excess MCAK (zeige KIF2C Antikörper) binding to chromatin to facilitate chromatin-nucleated spindle assembly.
MCAK (zeige KIF2C Antikörper) regulation of cytoplasmic and spindle-associated (zeige HAUS1 Antikörper) microtubules can be differentiated by Aurora B-dependent phosphorylation
results suggest an essential combined function of AurA (zeige AURKA Antikörper) and AurB in chromosome segregation and anaphase MT dynamics
Aurora B pathway is suppressed in the cytoplasm of Xenopus egg extract by phosphatases, but that it becomes activated by chromatin via a Ran-independent mechanism.
This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding different isoforms have been found for this gene.
, aurora 1
, aurora kinase B-Sv1
, aurora kinase B-Sv2
, aurora- and Ipl1-like midbody-associated protein 1
, aurora-related kinase 2
, aurora/IPL1-related kinase 2
, protein phosphatase 1, regulatory subunit 48
, serine/threonine kinase 12
, serine/threonine-protein kinase 12
, serine/threonine-protein kinase 5
, serine/threonine-protein kinase aurora-B
, aurora B
, aurora- and IPL1-like midbody-associated protein 1
, serine/threonine kinase 5
, aurora B kinase
, dAurora B
, Serine/threonine-protein kinase 12
, cellular island
, serine/threonine kinase a
, aurora kinase B
, serine/threonine-protein kinase 12-like
, Aurora/IPL1-related kinase 2-B
, Serine/threonine-protein kinase 12-B
, Serine/threonine-protein kinase aurora-B-B
, aurora kinase B-B
, aurora/IPL1-related kinase 2-B
, serine/threonine-protein kinase 12-B
, serine/threonine-protein kinase aurora-B-B