Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Weitere Synonyme anzeigen
Wählen Sie die gewünschte Spezies
Study found that Pldn is present at presynaptic terminals, where it localizes to synaptic microtubules and the cytoskeleton; while pallidin does not have major roles in synaptic growth, structure, or function under basal conditions, pallidin is crucial to maintain the releasable synaptic vesicle pool during conditions of high activity. Stability of Pldn depends crucially on the BLOC-1 subunits dysbindin (zeige DTNBP1 Proteine) and blos1 (zeige BLOC1S1 Proteine).
Results from a study on gene expression variability markers in early-stage human embryos shows that BLOC1S6 (PLDN) is a putative expression variability marker for the 3-day, 8-cell embryo stage.
PLDN is a direct target of RUNX1 (zeige RUNX1 Proteine) and its dysregulation is a mechanism for platelet dense granule deficiency associated with RUNX1 (zeige RUNX1 Proteine) haplodeficiency
Mecp2 regulates the expression of components belonging to the dysbindin (zeige DTNBP1 Proteine) interactome
no defects in the known components of pallidin-muted complex (BLOC-1)have been identif (zeige MUTED Proteine)ied in 142 patie (zeige BLOC1S1 Proteine)nts with HPS, suggesting that BLOC-1 function may be critical in humans.
Polycystin-2 (zeige PKD2 Proteine) requires IFT20 (zeige IFT20 Proteine)-GMAP210, the exocyst, and BLOC-1 for trafficking from endosomes to primary cilia.
We found 491 proteins sensitive to dysbindin (zeige DTNBP1 Proteine) and BLOC-1 loss of function
VAMP7 mediates fusion of BLOC-1-dependent transport carriers with melanosomes, illuminate SNARE recycling from melanosomes as a critical BLOC-3-dependent step.
Data suggest functional links between OCA2 and the BLOC-1, BLOC-2, and AP-3 protein complexes involved in melanosome biogenesis.
The identification of the feeble mutation led to our subsequent observations that AP-3 (zeige AP3B1 Proteine), as well as the BLOC-1 and BLOC-2 (zeige HPS6 Proteine) are essential for plasmacytoid dendritic cells signaling through TLR7 (zeige TLR7 Proteine) and TLR9 (zeige TLR9 Proteine).
This study demonstrated that Loss-of-function alleles of BLOC-1, Pldn(pa/pa), and Muted (zeige MUTED Proteine)(mu/mu) revealed that this complex acts as a brain-region-specific regulator of AP-3 (zeige AP3B1 Proteine).
pallidin may play a role in membrane fusion events required for melanosome biogenesis
BLOC-1, a novel complex containing this and muted (zeige MUTED Proteine) proteins involved in the biogenesis of melanosomes and platelet-dense granules
a Cappuccino frameshift mutation abolishes its ability to interact with pallidin-muted (zeige MUTED Proteine) complex (BLOC-1)in mice
The protein encoded by this gene may play a role in intracellular vesicle trafficking. It interacts with Syntaxin 13 which mediates intracellular membrane fusion. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
, BLOC-1 subunit 6
, biogenesis of lysosomal organelles complex-1, subunit 5, pallidin
, biogenesis of lysosome-related organelles complex 1 subunit 6
, pallid protein homolog
, syntaxin 13 binding protein 1
, syntaxin 13-interacting protein pallid
, pallidin homolog
, pallid protein
, syntaxin 13-interacting protein pallidin