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Human Polyclonal SKI Primary Antibody für FM, ELISA - ABIN1003140
Li, Turck, Teumer, Stavnezer: Unique sequence, ski, in Sloan-Kettering avian retroviruses with properties of a new cell-derived oncogene. in Journal of virology 1986
Show all 4 Pubmed References
A microRNA miR (zeige MLXIP Antikörper)-155 regulates transforming growth factor-beta TGF-beta-induced human coronary artery endothelial cells fibrogenic endothelial-mesenchymal transition via the regulator of TGF-beta (zeige TGFB1 Antikörper) signaling c-Ski to affect cardiac fibrosis, and miR (zeige MLXIP Antikörper)-155/c-Ski may represent novel biomarkers and therapeutic targets for cardiac fibrosis.
Study identified Ski as a functional tumor suppressor with frequent epigenetic inactivation in lung cancer.
Transforming Growth Factor beta inhibitor peptide P144 (zeige TCERG1 Antikörper) downregulates SKI and an upregulates SMAD7 (zeige SMAD7 Antikörper) at both transcriptional and translational levels in glioblastoma cell lines.
miR (zeige MLXIP Antikörper)-1908 had a positive role in scar formation by suppressing Ski-mediated inflammation and fibroblast proliferation in vitro and in vivo.
Overexpression of Ski wild type, but not S326D and S383D mutants inhibited centrosome amplification and cellular transformation induced by AURKA (zeige AURKA Antikörper).
our findings suggest that Ski represses TGF-b-induced EMT (zeige ITK Antikörper) and invasion by inhibiting SMAD (zeige SMAD1 Antikörper)-dependent signaling in non-small cell lung cancer
Ski regulates Hippo and TAZ (zeige TAZ Antikörper) signaling to suppress breast cancer progression.
Eight recurrent and three novel SKI mutations from eleven SGS (zeige FBN1 Antikörper) patients were located in the R-SMAD (zeige SMAD1 Antikörper) binding domain, except for one in the DHD domain.
acetaldehyde up-regulates COL1A2 (zeige COL1A2 Antikörper) by modulating the role of Ski and the expression of SMADs 3, 4, and 7.
c-Ski is an important regulator in the activation of CAFs and may serve as a potential therapeutic target to block breast cancer progression.
study reveals a critical mechanism by which TGFbeta (zeige TGFB1 Antikörper) controls TH17 cell differentiation and uncovers the SKI-SMAD4 (zeige SMAD4 Antikörper) axis as a potential therapeutic target for treating TH17-related diseases
our results demonstrate that SKI is an important regulator of hematopoietic stem cell activity and its overexpression leads to myeloproliferative disease.
Trnsgenic mice overexpressing chicken Ski (c-Ski) have marked decrease in adipose mass with skeletal muscle hypertrophy Results suggest Ski plays a major role in skeletal muscle metabolism and adipogenesis and hence influences risk of obesity and diabetes
After Qingyi Huaji treatment, Ski expression was reduced and pancreatic tumor growth slowed down significantly.
Satb2 (zeige SATB2 Antikörper) recruits Ski to the Ctip2 (zeige BCL11B Antikörper) locus, and Ski attracts histone deacetylases, thereby enabling the formation of a functional nucleosome remodeling and deacetylase repressor complex.
Data on expression of Ski suggest that Ski is involved in follicular development, oogenesis, ovulation, and luteinization. During the estrous cycle, Ski expression was apparent at proestrus and estrus, faint at metestrus, highest at diestrus.
The presented data support a new role for Ski in the mitotic process and in maintenance of genetic stability
Ski regulates several genetic programs and signalling pathways that regulate skeletal muscle and adipose mass to influence body composition development, suggesting that Ski may have a role in risk for obesity and metabolic disease.
Increased susceptibility to tumorigenesis of ski-deficient heterozygous mice
SnoN (zeige SKIL Antikörper) and Ski proteins are up-regulated during liver regeneration
This gene encodes the nuclear protooncogene protein homolog of avian sarcoma viral (v-ski) oncogene. It functions as a repressor of TGF-beta signaling, and may play a role in neural tube development and muscle differentiation.
, ski oncogene
, ski oncoprotein
, v-ski sarcoma viral oncogene homolog (avian)
, avian sarcoma viral (v-ski) oncogene homolog natural resistance-associated macrophage protein 1
, v-ski avian sarcoma viral oncogene-like protein
, Sloan-Kettering viral oncogene homolog
, ski sarcoma viral oncogene homolog
, v-ski sarcoma viral oncogene homolog