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anti-Human VEGFC Antikörper:
anti-Mouse (Murine) VEGFC Antikörper:
anti-Rat (Rattus) VEGFC Antikörper:
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Human Polyclonal VEGFC Primary Antibody für IHC (fro), IHC (p) - ABIN258871
Zampell, Yan, Avraham, Daluvoy, Weitman, Mehrara: HIF-1α coordinates lymphangiogenesis during wound healing and in response to inflammation. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012
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Human Polyclonal VEGFC Primary Antibody für IF (p), IHC (p) - ABIN731723
Zhuo, Jia, Song, Lu, Ding, Wang, Song, Fu, Luo: The CXCL12-CXCR4 chemokine pathway: a novel axis regulates lymphangiogenesis. in Clinical cancer research : an official journal of the American Association for Cancer Research 2012
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Human Polyclonal VEGFC Primary Antibody für IP, ELISA - ABIN541859
Krishnan, Kirkin, Steffen, Hegen, Weih, Tomarev, Wilting, Sleeman: Differential in vivo and in vitro expression of vascular endothelial growth factor (VEGF)-C and VEGF-D in tumors and its relationship to lymphatic metastasis in immunocompetent rats. in Cancer research 2003
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Human Monoclonal VEGFC Primary Antibody für ICC, IHC (fro) - ABIN438679
Moussai, Mitsui, Pettersen, Pierson, Shah, Suárez-Fariñas, Cardinale, Bluth, Krueger, Carucci: The human cutaneous squamous cell carcinoma microenvironment is characterized by increased lymphatic density and enhanced expression of macrophage-derived VEGF-C. in The Journal of investigative dermatology 2010
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Human Polyclonal VEGFC Primary Antibody für FACS, IHC (p) - ABIN650694
Yan, Zhu, Yu, Ji, Zhang, Ji, Yan, Chen, Liu, Yin, Lin: Expression of vascular endothelial growth factor C and chemokine receptor CCR7 in gastric carcinoma and their values in predicting lymph node metastasis. in World journal of gastroenterology : WJG 2004
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Rat (Rattus) Polyclonal VEGFC Primary Antibody für IP, ELISA - ABIN1589911
Maertens, Erpicum, Detry, Blacher, Lenoir, Carnet, Péqueux, Cataldo, Lecomte, Paupert, Noel: Bone marrow-derived mesenchymal stem cells drive lymphangiogenesis. in PLoS ONE 2014
These findings thus underscore a role for posterior cardinal (zeige CARD8 Antikörper) vein and VegfC in patterning the head kidney prior to organ assembly and function.
Vegfc acts through ERK (zeige MAPK1 Antikörper) to induce sprouting and differentiation of trunk lymphatic progenitors.
data not only reveal a non-canonical function of Mt2 (zeige MT2 Antikörper) in angiogenesis, but also propose Mt2 (zeige MT2 Antikörper) as a novel regulator of vegfc expression.
Vegfc signaling increases mafba (zeige MAFB Antikörper) expression to control downstream transcription
Vegfc is dispensable for facial lymphatic sprouting but not for the complete development of the facial lymphatic network.
In the embryo, phenotypes driven by increased Vegfc are suppressed in the absence of Ccbe1 (zeige CCBE1 Antikörper), and Vegfc-driven sprouting is enhanced by local Ccbe1 (zeige CCBE1 Antikörper) overexpression. Moreover, Vegfc- and Vegfr3 (zeige FLT4 Antikörper)-dependent Erk (zeige MAPK1 Antikörper) signaling is impaired in the absence of Ccbe1 (zeige CCBE1 Antikörper).
Vegfc has an essential role in lymphangiogenesis [review]
The parallel growth of motoneuron axons with the dorsal aorta depends on Vegfc/Vegfr3 (zeige FLT4 Antikörper) signaling in zebrafish.
Vegfc acts in two distinct modes during development: as a paracrine factor secreted from arteries to guide closely associated lymphatic vasculature and as an autocrine factor to drive migratory persistence during angiogenesis.
Rspo1-Wnt-VegfC-Vegfr3 signaling plays a crucial role as an endothelial-autonomous permissive cue for developmental angiogenesis.
VEGF-C and VEGF (zeige VEGFA Antikörper)-C156S genes have roles in the pro-lymphangiogenic growth factor therapy of lymphedema
Transcription of the vascular endothelial growth factor C gene (VEGF-C) and translation of the corresponding protein were significantly up-regulated in swine umbilical vein endothelial cells with classical swine fever virus acute infection.
No difference in bioactivity was detected between porcine relaxin-1 (zeige RLN1 Antikörper) and recombinant human relaxin-2 (zeige RLN1 Antikörper) in either mice or rats.
During progressive ischemia, functional and metabolic benefits of intramyocardial VEGF-C gene transfer were apparent. VEGF-C-induced collateral formation occurred at the site of gene transfer
SPARC (zeige SPARC Antikörper) expression was inversely associated with the degree of malignancy and it had a negative correlation with VEGF-C and VEGF-D (zeige Figf Antikörper) expression. Results suggest SPARC (zeige SPARC Antikörper) might function as a tumor suppressor inhibiting angiogenesis and lymphangiogenesis in ovarian cancer by reducing the expression of VEGF-C and VEGF-D (zeige Figf Antikörper).
VEGF-A/VEGF (zeige VEGFA Antikörper)-C analysis showed higher positivity in metastatic nodes and higher positivity in the surrounding negative nodes from positive cases in comparison with nonmetastatic patients.
this study shows that decidual NK cells facilitate the interaction between trophoblastic and endothelial cells via VEGF-C and HGF (zeige HGF Antikörper)
Lymphangiogenesis during tubulointerstitial fib (zeige CTGF Antikörper)rosis to be associated with increased expression of CTGF and VEGF-C in human obstructed nephropathy as well as in diabetic kidney disease. vitro, CTGF induced VEGF-C production in HK-2 cells, while CTGF siRNA suppressed transforming growth factor beta1-induced VEGF-C upregulation.
Smad4 (zeige SMAD4 Antikörper) expression negatively correlated with VEGF-A (zeige VEGFA Antikörper) and VEGF-C in colon cancer
study is the first to describe the mechanism of leptin (zeige LEP Antikörper)-promoted lymphangiogenesis by upregulating VEGF-C expression in chondrosarcomas.
Retroperitoneal tumour progression in EOC patients is associated with high VEGF-C expression.
Mechanistic investigations indicated that BDNF (zeige BDNF Antikörper) facilitated VEGF-C-dependent lymphangiogenesis through the MEK (zeige MAP2K1 Antikörper)/ERK (zeige EPHB2 Antikörper)/mTOR (zeige FRAP1 Antikörper) signaling pathway.
no difference in the levels of VEGF-A (zeige VEGFA Antikörper), VEGF-C, and VEGF-D (zeige Figf Antikörper) in pre-eclampsia compared to normotensive pregnant women stratified by HIV status
Results has shown that VEGF-C was highly expressed in non-small cell lung cancer (NSCLC) tissues and metastatic lymph nodes. VEGF-C expression levels was significantly correlated with lymph node metastasis in NSCLC. Along with CXCR4 (zeige CXCR4 Antikörper), VEGF-C might synergically promote lymphatic metastasis in lung cancer and might be a clinical predictor of lymph node metastasis in NSCLC patients.
As shown in mouse model of kidney fibrosis CTGF (zeige CTGF Antikörper) is significantly involved in fibrosis-associated renal lymphangiogenesis through regulation of, and direct interaction with, VEGF-C.
Fluid shear stress regulates vascular remodeling via VEGFR-3 (zeige FLT4 Antikörper) activation, independently of its ligand, VEGF-C, in the uterus during pregnancy.
A novel heparin conjugate (LHbisD4) is shown to prevent lymphangiogenesis by blocking the vascular endothelial growth factor C (VEGF-C) induced signaling pathway.
lymphangiogenesis is regulated by two distinct proteolytic mechanisms of ligand activation: one in which VEGFC activation by ADAMTS3 (zeige Adamts2 Antikörper) and CCBE1 (zeige CCBE1 Antikörper) spatially and temporally patterns developing lymphatics, and one in which VEGFD (zeige Figf Antikörper) activation by a distinct proteolytic mechanism may be stimulated during inflammatory lymphatic growth
These results reveal an unexpected role for VEGF-C, a major lymphangiogenic growth factor, in the transition to fetal liver erythropoiesis.
Results suggest that interleukin-6 (IL-6 (zeige IL6 Antikörper)) increases VEGF-C induction and lymphangiogenesis may involve, at least in part, Src (zeige SRC Antikörper)-FAK (zeige PTK2 Antikörper)-STAT3 (zeige STAT3 Antikörper) cascade in lymphatic endothelial cells (LECs).
Data show that heparanase-1 (HPA-1 (zeige HPSE Antikörper)) induced shedding of heparan sulfate chain from syndecan-1 (SDC-1 (zeige SDC1 Antikörper)) facilitated the release of vascular endothelial growth factor C (VEGF-C) from SDC-1 (zeige SDC1 Antikörper)/VEGF-C complex into the medium of hepatocarcinoma cell.
Data show that in the MCF-7 breast cancer cell line, only MT1X (zeige MT1X Antikörper) metallothioneins (MTs (zeige NEU2 Antikörper)) positively correlated with vascular endothelial growth factor C (VEGFC).
The findings in this study strongly suggest the following: i) that VEGF-C promotes the proliferative activity and migratory ability of mesenchymal stem cell ; and ii) VEGF-C and Tgfb (zeige TGFB1 Antikörper) reciprocally regulate mesenchymal stem cell commitment to differentiation into lymphatic endothelial or osteoblastic phenotypes, respectively.
The authors show that VEGF-C is necessary for perinatal lymphangiogenesis, but required for adult lymphatic vessel maintenance only in the intestine.
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.
vascular endothelial growth factor C
, vascular endothelial growth factor c
, FLT4 ligand DHM
, vascular endothelial growth factor-related protein
, flt4 ligand
, vascular endothelial growth factor C isoform 129
, vascular endothelial growth factor C isoform 184