Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Human HGF Antikörper:
anti-Mouse (Murine) HGF Antikörper:
anti-Rat (Rattus) HGF Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Mouse (Murine) Polyclonal HGF Primary Antibody für WB - ABIN3042443
Zhang, Wang, Ma, Liu, Zhang, Zhu: Effect of herba centellae on the expression of HGF and MCP-1. in Experimental and therapeutic medicine 2013
Show all 11 Pubmed References
Human Polyclonal HGF Primary Antibody für IF (p), IHC (p) - ABIN736551
Yu, He, Jiang, He, Fan, Wang, Geng, Dong: Expression and tissue distribution of hepatocyte growth factor (HGF) and its receptor (c-Met) in alpacas (Vicugna pacos) skins associated with white and brown coat colors. in Acta histochemica 2015
Show all 5 Pubmed References
Cow (Bovine) Polyclonal HGF Primary Antibody für IHC, WB - ABIN2781816
Kitajima, Ide, Ohtsuka, Miyazaki: Induction of hepatocyte growth factor activator gene expression under hypoxia activates the hepatocyte growth factor/c-Met system via hypoxia inducible factor-1 in pancreatic cancer. in Cancer science 2008
Show all 6 Pubmed References
Human Polyclonal HGF Primary Antibody für IHC (p), ELISA - ABIN544641
Toiyama, Yasuda, Saigusa, Matushita, Fujikawa, Tanaka, Mohri, Inoue, Goel, Kusunoki: Co-expression of hepatocyte growth factor and c-Met predicts peritoneal dissemination established by autocrine hepatocyte growth factor/c-Met signaling in gastric cancer. in International journal of cancer. Journal international du cancer 2012
Show all 4 Pubmed References
Human Polyclonal HGF Primary Antibody für IHC (f), ICC - ABIN966282
Gohda, Tsubouchi, Nakayama, Hirono, Sakiyama, Takahashi, Miyazaki, Hashimoto, Daikuhara: Purification and partial characterization of hepatocyte growth factor from plasma of a patient with fulminant hepatic failure. in The Journal of clinical investigation 1988
Show all 3 Pubmed References
Human Monoclonal HGF Primary Antibody für IHC (p), IHC - ABIN438999
Puzio-Kuter, Laddha, Castillo-Martin, Sun, Cordon-Cardo, Chan, Levine: Involvement of tumor suppressors PTEN and p53 in the formation of multiple subtypes of liposarcoma. in Cell death and differentiation 2015
Show all 2 Pubmed References
Human Polyclonal HGF Primary Antibody für FACS, IHC (p) - ABIN388462
Ryugo, Sawa, Ono, Fukushima, Aleshin, Mizuno, Nakamura, Matsuda: Myocardial protective effect of human recombinant hepatocyte growth factor for prolonged heart graft preservation in rats. in Transplantation 2004
Show all 7 Pubmed References
Human Monoclonal HGF Primary Antibody für ELISA, IHC - ABIN251141
Lin, Teo, Lam, Jeyaseelan, Wang: MicroRNA-10b pleiotropically regulates invasion, angiogenicity and apoptosis of tumor cells resembling mesenchymal subtype of glioblastoma multiforme. in Cell death & disease 2012
Human Polyclonal HGF Primary Antibody für PLA, WB - ABIN516424
Ogunwobi, Liu: Hepatocyte growth factor upregulation promotes carcinogenesis and epithelial-mesenchymal transition in hepatocellular carcinoma via Akt and COX-2 pathways. in Clinical & experimental metastasis 2011
Human Polyclonal HGF Primary Antibody für ELISA, WB - ABIN561254
Bouazza, Kratassiouk, Gjata, Perie, Lacau St Guily, Butler-Browne, Svinartchouk: Analysis of growth factor expression in affected and unaffected muscles of oculo-pharyngeal muscular dystrophy (OPMD) patients: a pilot study. in Neuromuscular disorders : NMD 2009
Hepatocyte growth factor (HGF) levels could determine the relationship of hemoglobin concentration with handgrip strength in elderly Japanese men aged 60-69 years.
While novel diagnostic tumour markers are urgently needed, the examined potential tumour markers, with the exception of PIVKAII seem to be inadequate for diagnosing HCC in ALC \
Serum level of HGF in prostate cancer.
miR-449a suppresses hepatocellular carcinoma tumorigenesis by down-regulating activity in the c-Met/ERK pathway.
widely stained in sclerosing stromal tumours of the ovary
This novel study, in HIV-positive, preeclampsia, and normotensive pregnancies, demonstrates that HGF was two-fold higher in conducting compared to exchange villi irrespective of the pregnancy type. HIV infection does not influence HGF expression within the conducting and exchange villi.
CAFderived HGF promotes angiogenesis.
These results suggest that gastric cancer progression is not associated with a unique signaling pathway and that a feedback loop may exist between the HGF/c-Met and Notch1 signaling pathways, which may result in therapeutic resistance.
a higher HGF serum level during hemodialysis treatment is associated with a slower loss of residual renal function
prolonged treatment of single HGF/c-Met or Hh inhibitor leads to resistance to these single inhibitors, likely because the single c-Met treatment leads to enhanced expression of Shh, and vice versa. Targeting both the HGF/c-Met and Hh pathways simultaneously overcame the resistance to the single-inhibitor treatment and led to a more potent antitumor effect in combination with the chemotherapy treatment.
TGF-beta negatively controls the HGF/c-MET pathway by regulating of stemness in glioblastoma.
Reduction of fibroblast size upregulates HGF expression, which in turn contributes to loss of collagen, a prominent feature of aged skin.
Results of our present study suggest that both IL-6 and HGF derived from Cancer-associated fibroblasts (CAFs)could contribute to the intratumoral androgen metabolism in ER-negative breast carcinoma patients.
Hepatocyte growth factor as cardiovascular hormone: role of HGF in the pathogenesis of cardiovascular disease. Review.
this study shows that decidual NK cells facilitate the interaction between trophoblastic and endothelial cells via VEGF-C and HGF
We identify HGF, acting through the c-Met receptor, as the key polarity-inducing morphogen, which acts to activate b1-integrin-dependent adhesion. HGF and ECM-derived integrin signals co-operate via a c-Src-dependent inhibition of the RhoA-ROCK1 signalling pathway via p190A RhoGAP.
High glucose activated Met receptor in HK2 cells independently of HGF, via induction of integrin a5b1 and downstream signaling. This mode of Met activation was associated with tubular cell damage and apoptosis and it may represent a novel pathogenic mechanism and a treatment target in diabetic nephropathy.
results show that HGF was involved in regulating Chk1 phosphorylation, and further demonstrate that AKT activity was responsible for this HGF-induced Chk1 phosphorylation.
Lymph node metastasis is strongly associated with expression status of HGF and CD133 at the deep invasive front, suggesting the usefulness of these proteins as independent predictive markers of lymph node metastasis in early gastric cancer.
EGF-mediated lysosome trafficking, protease secretion, and invasion is regulated by the activity of p38 mitogen activated protein kinase (MAPK) and sodium hydrogen exchangers (NHEs). Interestingly, EGF stimulates anterograde lysosome trafficking through a different mechanism than previously reported for HGF, suggesting that there are redundant signaling pathways that control lysosome positioning
c-Fos is necessary for HGF-mediated gene regulation and cell migration in Schwann cells.
CBD-HGF combined with hydrogel scaffold may be promising for the treatment of serious SCI.
these results suggested that HGF may exert beneficial effects on type II diabetesinduced chronic renal failure via regulation of the NFkappaB signaling pathway.
HGF is beneficial for bone regeneration via increased expression of BMP-2, which leads to neovascularization and bone regeneration through regulation of the NF-kappaB signaling pathway.
these findings highlight the relevance of cross-species protein interactions between murine feeder cells and human epithelial cells in 3T3-J2 co-culture and demonstrate that STAT6 phosphorylation occurs in response to MET activation in epithelial cells. However, STAT6 nuclear translocation does not occur in response to HGF, precluding the transcriptional activity of STAT6.
These results indicate that expression and production of HGF are regulated in a species-specific adipogenic differentiation-dependent manner and suggest that the decrease in HGF mRNA in mouse differentiated adipocytes is, at least in part, mediated by differentiation-dependent loss of its stability.
Mesenchymal stem cells microvesicles stabilization of endothelial barrier function is partly mediated by hepatocyte growth factor.
HGF supports hindlimb motor neurons through c-Met; CNTF supports subsets of axial motor neurons through CNTFRalpha; and Artemin acts as the first survival factor for parasympathetic preganglionic motor neurons through GFRalpha3/Syndecan-3 activation.
Study used biochemical and morphological analyses to demonstrate that two discrete intracellular signaling pathways underlie distinct HGF-induced biological outcomes in developing neocortical neurons. Further, it identified a key developmental epoch, corresponding to the period of dendritic outgrowth and synaptogenesis, during which HGF stimulation elicits maximal activation of MET in the neocortex.
Our results show that BMF-derived IL-6/HGF and cancer cell-derived TGF-b1 mediate the interactions between bone marrow-derived myofibroblasts and gastric cancer cells, which regulate cancer stemness and promote tumorigenesis.
this study demonstrates an important role for HGF in the protective effects mediated by mesenchymal stromal cells in vivo in the bleomycin model of idiopathic pulmonary fibrosis
HGF displays an antioxidant response by inducing the glutathione-related protection system.
this study revealed that HB-EGF as well as HGF inhibited BDL-induced cholestatic liver injury by predominantly exerting acute cytoprotective and chronic antifibrotic effects, respectively.
The results suggest that PGRN may affect the differentiation of retinal precursor cells to photoreceptor cells through the HGF receptor signaling pathway.
Exposure of macrophages to cyclooxygenase (COX-2) inhibitors RhoA and LA-4 cells to antagonists of prostaglandin E2 (PGE2) receptor , PGD2 receptors or the hepatocyte growth factor (HGF) receptor c-Met (PHA-665752), reversed EMT inhibition by the conditioned medium
Notch signaling plays an important role in regulation of interactions between TGF-beta and HGF signaling pathways in proximal tubule epithelial cells
inhibition of PPARgamma activity reversed the expression of transforming growth factor-beta (TGF-beta), interleukin (IL)-10, and hepatocyte growth factor (HGF).
Molecular and functional studies revealed that ectopic Met expression in limb mesenchyme does not alter HGF expression patterns and levels, but impairs HGF bioavailability
These data strongly indicate that paracrine Met signaling can control the function of luminal progenitors and modulate their fate during mammary development and tumorigenesis.
Results confirm the prodevelopmental actions of activin A and indicate that CTGF may also function as an embryokine by regulating the number of ICM cells in the blastocyst and altering gene expression. Low concentrations of HGF were inhibitory to development.
SNPs within bovine HGF gene were significantly associated with growth traits. This will provide a background for application of bovine HGF gene in the selection program in Chinese cattle.
Treatment of the bovine satellite cells (BSC) with ephrin-A5 causes a reduction in velocity with a concomitant increase in directed migration. Treatment of BSC with hepatocyte growth factor had no immediate effect on cell motility or migration.
HGF transiently increases gene transcription of angiotensin-converting enzyme
acute pulmonary embolism associated with an enhanced HGF expression in the lungs, the right ventricle, and the liver
Combined administration of mesenchymal stem cells overexpressing IGF-1 and HGF enhances neovascularization but moderately improves cardiac regeneration in a porcine model.
In an animal model of acute myocardial infarction relevant to human disease, intracoronary administration of IGF-1/hepatocyte growth factor (HGF) is a practical and effective strategy to reduce pathological cardiac remodeling.
the truncated variant of gHGF (a double mutant of N-terminal hairpin and first kringle domains of gHGF, K132E and G134E, gmNK1) protein fused with His6 tag, the molecular weight of which was about 20.0kDa, which was expressed in Escherichia coli BL21 (DE3) and purified with Ni(2+)-affinity chromatography.gmNK1 inhibited protein expression levels of fibrosis-related Col I and alpha-SMA in TGF-beta1-activated HSC-T6 cells
Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms.
fibroblast-derived tumor cytotoxic factor
, hepatocyte growth factor
, lung fibroblast-derived mitogen
, scatter factor
, hepapoietin A
, HGF alpha-chain
, hepatocyte growth factor /scatter factor