TAP2 ELISA Kit

Beschreibung des Gens

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces two products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules.

Alternative names and synonyms associated with TAP2

• transporter 2, ATP binding cassette subfamily B member (TAP2) ELISA Kit
• transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) (Tap2) ELISA Kit
• transporter 2, ATP binding cassette subfamily B member (Tap2) ELISA Kit

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Bezeichner auf Proteinebene für TAP2

ABC transporter, MHC 2 , ATP-binding cassette, sub-family B (MDR/TAP), member 3 , antigen peptide transporter 2 , peptide supply factor 2 , peptide transporter PSF2 , peptide transporter involved in antigen processing 2 , really interesting new gene 11 protein , transporter 2, ABC (ATP binding cassette) , ATP dependent transport protein family member , ATP-binding cassette sub-family B member 3 , histocompatibility antigen modifier 2 , APT2 , Transporter 2 ABC (ATP binding cassette) , ABC-transporter , transporter 2, ABC(ATP binding cassette) , transporter 2, ATP-binding cassette, sub-family B