Angiomotin Protein (AMOT) (AA 1-1126) (His tag)

Produktnummer ABIN7564759

Produktdetails

Target: Angiomotin (AMOT)

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-1126

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Angiomotin Protein ist gelabelt mit His tag.

Verwendungszweck: Custom-made recombinant Amot Protein expressed in mammalian cells.

Sequenz: MRSSDDQPSG GTTVLQRLLQ EQLRYGNPSE NRSLLAIHQQ ATGNSSPFST GSGNQGPQND VLSSQDHHQQ QLVAHPARQE PQGQEIQSEN GVMEKQLSPR MQNNEELPTY EEAKVQSQYF RGQQHASVGA AFYVTGVTNQ KMRTEGRPSV QRLTPGKMHQ DEGLRDLKQG HVRSLSERLM QMSLATSGVK AHPPVTSAPL SPPQPNDLYK NATSSSEFYK AQGPPPSQHS LKGMEHRGPP PEYPFKGVPS QSVVCKSQEP GHFYSEHRLN QPGRTEGQLM RYQHPPEYGA ARATQDISSL SLSARNSQPH SPTSSLTAGA SSLPLLQSPP STRLPPGQHL VSNQGDHSAH LSRHQQHLLS SQSHQGDHYR HAQASLTSAQ QQPGEAYSAM PRAQQSASYQ PMPADPFAMV SRAQQMVEIL SDENRNLRQE LDGCYEKVAR LQKVETEIQR VSEAYENLVK SSSKREALEK AMRNKLEGEI RRMHDFNRDL RDRLETANKQ LAEKEYEGSE DTRKTISQLF AKHKENQREK EKLEAELATA RSTNEDQRRH IEIRDQALSN AQAKVVKLEE ELKKKQVYVD KVEKMQQALV QLQAACEKRE QLEHRLRTRL ERELESLRIQ QRQGNSQPTN ASEYNAAALM ELLREKEERI LALEADMTKW EQKYLEENVM RHFALDAAAT VAAQRDTTVI SHSPNTSYDT ALEARIQKEE EEILMANKRC LDMEGRIKTL HAQIIEKDAM IKVLQQRSRK EPSKTEQLSS MRPAKSLMSI SNAGSGLLAH SSTLTGAPIM EEKRDDKSWK GSLGVLLGGD YRVEPVPSTP SPVPPSTPLL SAHSKTGSRD CSTQTERGPE STKTAAVTPI SAPMAGPVAA AAPAAAINAT AATNTATAAT NTTIMVAAAP VAVAAVAAPA AAAATPSPAN AAALAAAAAP ATSVSAATSV SAANSISPAA PVAPAAVVPP AAPVSPAAAV QIPAAASLTP ATVSPTAATA TAAVAAATTA AITAAAAAAT TAIQVAPATS APVPSPASIP APATAQASAP TPTQASTPAP TEPPSPVPTP TPALVQTEGP ANPGASSGPR RLSTPNLMCN PDKPDAPAFH SSTLERKTPI QILGQEPDAE MVEYLI Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Spezifität: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Produktmerkmale: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Reinheit: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Güteklasse: custom-made

Anwendungsinformationen

Applikationshinweise: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C.

Haltbarkeit: 12 months

Antigendetails

Target: Angiomotin (AMOT)

Andere Bezeichnung: Amot (AMOT Produkte)

Hintergrund: Angiomotin,FUNCTION: Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions (By similarity). {ECO:0000250}.

Molekulargewicht: 120.9 kDa

UniProt: Q8VHG2

AlphaFold: Q8VHG2

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size