AGBL3 Protein (AA 1-1006) (His tag)

Produktnummer ABIN7564550

Produktdetails

Target: AGBL3 (ATP/GTP Binding Protein-Like 3 (AGBL3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-1006

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses AGBL3 Protein ist gelabelt mit His tag.

Verwendungszweck: Made-to-order recombinant Agbl3 Protein expressed in mammalian cells.

Sequenz: MSEDSEEEDY SDRSISDDDD LDEDSFMKFV SDDIHPCTLL AADSIGDPFF PRTTQILLEY QLGRWVPRLR GPRDLYGVSS SGPLSPTRWP YHCEVIDEKV QHIEWTPFVP EPVYVPTGLE IEPVYPNSKE DTVVYLAEDD HLCKAYKEPC FVYSRVGGNR TSLKQPVDNC DNTLVFEARF ESGNLQKVVK VADHEYELTV RPDLFTNKHT QWYYFQVTNT QAEIVYRFTI VNFTKPASLY NRGMKPLFYS EKEAKTHNIG WQRIGDQIKY YKNNLGQDGR HFFSLTWTFQ FPHSQDTCYF AHCYPYTYSN LQEYLSGINS DPVRSKFCKI RVLCHTLARN MVYVLTITTP LKTSDSKRKA VILTARVHPG ETNSSWIMKG FLDYILGDSS DARLLRDTFI FKVVPMLNPD GVIVGNYRCS LAGRDLNRNY TSLLKESFPS VWYTRNMINR LMEKREVILY CDLHGHSRKQ NIFMYGCDGS SRSKTKGLYL QQRIFPLMLS KNCPNIFSFS ACKFNVQKSK EGTGRVVMWK MGIRNSFTLE ATFCGSTLGN KRGTHFGTKD LESMGYHFCD SLLDYCDPDR SKYYQCLKEL EEMEKHLSSE RVSDNTDTSL VEISLDVESS SRGSDSSESN DTQTYLLKVT SQARNKKKYL KTKRERNAIL ANCQNNMQEV YGKEHLLQRH DESNSDGNDP RIDAPDVYVA HCFRRPLPNQ GVVKIPGQRF YPGKTWSSSQ RMIKSLNKDH RTCILETCKN PIQEVQSRGI NIHESCFKMA KCPMNKRPSH WIEKTRIPTE SHHQLKSKAK RCSSFQSKRT GTNWTDDEKR IYRDKRIAQT QEILKYLLPI VESSQNRKST QMNNLINPIA NLQQHQLIPT ACINRRRYSI PWTPTRNLPF KAQRNLMTDT SEWLQSVPLG SFESLLPLCN LQKKTKHFEL WGKKAKDVQL ATSQWEAVPL SSNMDASIIR GNSVLQPKEF TMRSSKQRIP YLTKTSKKPS ESDGLLTFQL KIHRNS Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Spezifität: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Produktmerkmale: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Reinheit: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Güteklasse: custom-made

Anwendungsinformationen

Applikationshinweise: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C.

Haltbarkeit: 12 months

Antigendetails

Target: AGBL3 (ATP/GTP Binding Protein-Like 3 (AGBL3))

Andere Bezeichnung: Agbl3 (AGBL3 Produkte)

Hintergrund: Cytosolic carboxypeptidase 3 (EC 3.4.17.-) (ATP/GTP-binding protein-like 3) (Protein deglutamylase CCP3),FUNCTION: Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins (PubMed:25103237). Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein (PubMed:25103237). Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate (PubMed:25103237). Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK (PubMed:25103237). May catalyze the hydrolysis of aspartate from the carboxy-terminus of target proteins (PubMed:25103237). Does not show detyrosinase or deglycylase activities from the carboxy-terminus of target proteins (PubMed:25103237). {ECO:0000269|PubMed:25103237}.

Molekulargewicht: 116.4 kDa

UniProt: Q8CDP0

AlphaFold: Q8CDP0