Multicilin Protein (AA 1-379) (His tag)

Produktnummer ABIN7557319

Produktdetails

Target: Multicilin (MCIDAS) (Multiciliate Differentiation and DNA Synthesis Associated Cell Cycle Protein (MCIDAS))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-379

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Multicilin Protein ist gelabelt mit His tag.

Verwendungszweck: Made-to-order recombinant Mcidas Protein expressed in mammalian cells.

Sequenz: MQACEGSAAG RRAFDSICPN RMLDLSRRTL GKPGKPERKF VPSWKSFSGC GGGSPVAVYE DPPDAEPAPL PALTTIDLQD LADCTSLLGT EASPSGDSSA SQNPSLQTEE DFNLQNFRDA MDDLIADSSS LMSPPLTNSD FPFSPCDVSS FGSCLSPSLD PPALGSPDLP PPPTEQYWKE VADQNQRALG TALIENNQLH VTLTQKQEEI ASLRERNVQL KELASRTRHL ASVLDKLMIT QSPAEPFQIK ATTKRSLEEL FCAAGQAGQG CAEVDAILRD ISQRCEEALH NRDPKRPRLQ PEPDSKDCSS RNLHGAFRGL RTDCSASSVN LSHSELEEGG SFSTPIRSHS TIRTLAFPQG KAFTIRTVTG GYKFRWVPS Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Spezifität: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Produktmerkmale: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Reinheit: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Güteklasse: custom-made

Anwendungsinformationen

Applikationshinweise: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C.

Haltbarkeit: 12 months

Antigendetails

Target: Multicilin (MCIDAS) (Multiciliate Differentiation and DNA Synthesis Associated Cell Cycle Protein (MCIDAS))

Andere Bezeichnung: Mcidas (MCIDAS Produkte)

Hintergrund: Multicilin (Multiciliate differentiation and DNA synthesis-associated cell cycle protein) (McIdas protein) (Protein Idas),FUNCTION: Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1. {ECO:0000250|UniProtKB:D6RGH6, ECO:0000250|UniProtKB:Q08B36}.

Molekulargewicht: 41.1 kDa

UniProt: Q3UZ45

AlphaFold: Q3UZ45