SYTL4 Protein (AA 1-673) (His tag)

Produktnummer ABIN7556199

Produktdetails

Target: SYTL4 (Synaptotagmin-Like 4 (SYTL4))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-673

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SYTL4 Protein ist gelabelt mit His tag.

Verwendungszweck: Made-to-order recombinant Sytl4 Protein expressed in mammalian cells.

Sequenz: MSEILDLSFL SEMERDLILG VLQRDEELRK ADEKRIRRLK NELLEIKRKG AKRGSQHYSD RTCARCQEGL GRLIPKSSTC VGCNHLVCRE CRVLESNGSW RCKVCSKEIE LKKATGDWFY DQKVNRFDYR TGSEIIRMSL RQKPAVNKRE TAGQSLLQQT QMGDIWPGRR IIQEQQQREQ SVLFEVPKTR SGKSALEAES ESLDSYTADS DSTSRRDSLD KSGLFPEWKK MSAPKSQVEK EIPPGNQNAV CGDEGDMVFK KNTKKVLRPS EYTKSVIDLR PEDVAQESGI LGDRSKSVPG LSVDMEEEEE EEEDIDHLVK LHRQKLARGS MQSGSSMSTL GSIMSIYSEA GDFGNISVTG KIAFSLKFEQ KTQTLVIHVK ECHQLAYADE AKKRSNPYVK TYLLPDKSRQ GKRKTSIKRD TINPLYDETF RYEISESLLA QRTLQFSVWH HGRFGRNTFL GEAEVHMDSW KLDKKLDHCL PLHGKISTES SPGLPAHKGE LVVSLKYIPA SKLPVGGDRK KSKGGEGGEL QVWIKEAKNL TAAKSGGTSD SFVKGYLLPM RNKASKRKTP VMKKTLSPHY NHTFVYNGVR LEDLQHMCLE LTVWDREPLA SNDFLGGVRL GVGTGISNGE VVDWMDSTGE EVSLWQKMRQ YPGSWAEGTL QLRSSMVKQK LGV Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.

Spezifität: If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.

Produktmerkmale: Key Benefits:

• Made to order protein - from design to production - by highly experienced protein experts.
• Protein expressed in mammalian cells and purified in one-step affinity chromatography
• The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
• State-of-the-art algorithm used for plasmid design (Gene synthesis).

This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

If you are not interested in a full length protein, please contact us for individual protein fragments.

The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.

Reinheit: > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

Güteklasse: custom-made

Anwendungsinformationen

Applikationshinweise: We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The buffer composition is at the discretion of the manufacturer.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C.

Haltbarkeit: 12 months

Antigendetails

Target: SYTL4 (Synaptotagmin-Like 4 (SYTL4))

Andere Bezeichnung: Sytl4 (SYTL4 Produkte)

Hintergrund: Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin),FUNCTION: Modulates exocytosis of dense-core granules and secretion of hormones in the pancreas and the pituitary. Interacts with vesicles containing negatively charged phospholipids in a Ca(2+)-independent manner. {ECO:0000269|PubMed:12590134}.

Molekulargewicht: 76.0 kDa

UniProt: Q9R0Q1

AlphaFold: Q9R0Q1

Pathways: Negative Regulation of Hormone Secretion