PVRL4 Protein (AA 32-349) (Fc Tag)
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- Target Alle PVRL4 Proteine anzeigen
- PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 32-349
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses PVRL4 Protein ist gelabelt mit Fc Tag.
- Sequenz
- AA 32-349
- Reinheit
- >95 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Less than 0.1 EU per μg by the LAL method.
- Top Product
- Discover our top product PVRL4 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handhabung
- Please avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
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- Target
- PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))
- Andere Bezeichnung
- Nectin-4 (PVRL4 Produkte)
- Hintergrund
- Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50 % , 49 % and 86 %o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.
- Molekulargewicht
- 60.5 kDa
- NCBI Accession
- NP_112178
- Pathways
- Cell-Cell Junction Organization
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