IL18R1 Protein (AA 19-329) (Fc Tag)

Produktnummer ABIN6964389

Produktdetails

Target: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 19-329

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses IL18R1 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Human IL18RA Protein with C-terminal human Fc tag

Spezifität: IL18RA (Ala19-Arg329) hFc (Glu99-Ala330)

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Andere Bezeichnung: IL18RA (IL18R1 Produkte)

Hintergrund: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

Molekulargewicht: predicted molecular mass of 61.9 kDa after removal of the signal peptide.The apparent molecular mass of IL18RA-hFc is 55-70 kDa due to glycosylation.

UniProt: Q13478