HDAC8 Protein (AA 1-377) (His tag)
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- Target Alle HDAC8 Proteine anzeigen
- HDAC8 (Histone Deacetylase 8 (HDAC8))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-377
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Spezies
- Human
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Quelle
- Baculovirus infected Insect Cells
- Aufreinigungstag / Konjugat
- Dieses HDAC8 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- MEMPEEPANS GHSLPPVYIY SPEYVSICDS LVKVPKRASM VHSLIEAYAL HKQMRIVKPK VASMEEMATF HTDAYLQHLQ KVSQEGDEDH PDSIEYGLGY DCPATEGIFD YAAAIGGGTI TAAQCLIDGK CKVAINWSGG WHHAKKDEAS GFCYLNDAVL GILRLRRKFD RILYVDLDLH HGDGVEDAFS FTSKVMTVSL HKFSPGFFPG TGDMSDVGLG KGRYYSVNVP IQDGIQDEKY YHICESVLKE VYQAFNPKAV VLQLGADTIA GDPMCSFNMT PVGIGKCLKY VLQWQLATLI LGGGGYNLAN TARCWTYLTG VILGKTLSSE IPDHEFFTAY GPDYVLEITP SCRPDRNEPH RIQQILNYIK GNLKHVVHHH HHH
- Reinheit
- > 90 % by SDS - PAGE
- Endotoxin-Niveau
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product HDAC8 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- HDAC8 (Histone Deacetylase 8 (HDAC8))
- Andere Bezeichnung
- Hdac8 (HDAC8 Produkte)
- Hintergrund
- Hdac8, also known as histone deacetylase 8 isoform 1, is a member of the class I Histone Deacetylases. Its specific inhibition reduces gene expression and production of proinflammatory cytokines in vitro and in vivo. It expressed in the renal epithelial cells of the mouse kidney. Its activity contributes to renal protection and functional recovery and is required for renal regeneration after AKI. Recombinant mouse Hdac8, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molekulargewicht
- 42.5kDa (383aa) 40-57kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_081658
- UniProt
- Q8VH37
- Pathways
- Cellular Glucan Metabolic Process
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