TRIM24 Protein (AA 891-1012, partial) (His-SUMO Tag)
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- Target Alle TRIM24 Proteine anzeigen
- TRIM24 (Tripartite Motif Containing 24 (TRIM24))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 891-1012, partial
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses TRIM24 Protein ist gelabelt mit His-SUMO Tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- KKKTEGLVKL TPIDKRKCER LLLFLYCHEM SLAFQDPVPL TVPDYYKIIK NPMDLSTIKK RLQEDYSMYS KPEDFVADFR LIFQNCAEFN EPDSEVANAG IKLENYFEEL LKNLYPEKRF PK
- Aufreinigung
- SDS-PAGE
- Reinheit
- > 90 %
- Top Product
- Discover our top product TRIM24 Protein
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Tripartite Motif Containing 24 (TRIM24) (AA 1-1050) protein (GST tag)
TRIM24 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Tripartite Motif Containing 24 (TRIM24) (AA 896-1014) protein (His tag)TRIM24 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Tripartite Motif Containing 24 (TRIM24) (AA 891-1012), (partial) protein (His tag)TRIM24 Spezies: Human Wirt: Hefe Recombinant > 90 % SDS
Tripartite Motif Containing 24 (TRIM24) (AA 862-980) protein (His tag,DYKDDDDK Tag)TRIM24 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Bind, ScA
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Lagerung
- -80 °C,4 °C,-20 °C
- Informationen zur Lagerung
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- TRIM24 (Tripartite Motif Containing 24 (TRIM24))
- Andere Bezeichnung
- TIF1A (TRIM24 Produkte)
- Hintergrund
- Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP53 levels. Up-regulates ligand-dependent transcription activation by AR, GCR/NR3C1, thyroid hormone receptor (TR) and ESR1. Modulates transcription activation by retinoic acid (RA) receptors, including RARA. Plays a role in regulating retinoic acid-dependent proliferation of hepatocytes .
- Molekulargewicht
- 30.47 kDa
- UniProt
- O15164
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