MARCH8 Protein (Transcript Variant 7) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2725494

Produktdetails

Target: MARCH8 (Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 7

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses MARCH8 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human MARCH8 (transcript variant 7) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: MARCH8 (Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8))

Andere Bezeichnung: March8 (MARCH8 Produkte)

Synonyme: MARCH-VIII Protein, MIR Protein, RNF178 Protein, c-MIR Protein, zgc:171495 Protein, 1300017E09Rik Protein, Mir Protein, Mar-08 Protein, MARCH8 Protein, membrane associated ring-CH-type finger 8 Protein, membrane-associated ring finger (C3HC4) 8 Protein, membrane associated ring-CH-type finger 8 L homeolog Protein, MARCH8 Protein, march8 Protein, March8 Protein, march8.L Protein

Hintergrund: MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153] Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Apr 2010]

Molekulargewicht: 32.8 kDa

NCBI Accession: NP_001002266