LZTS2 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2725089

Produktdetails

Target: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses LZTS2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human LZTS2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Andere Bezeichnung: Lzts2 (LZTS2 Produkte)

Synonyme: lapser1 Protein, MGC89253 Protein, si:dkey-250a11.1 Protein, LAPSER1 Protein, BC014695 Protein, mKIAA1813 Protein, Lapser1 Protein, leucine zipper, putative tumor suppressor 2 Protein, leucine zipper tumor suppressor 2 Protein, leucine zipper, putative tumor suppressor 2a Protein, leucine zipper, putative tumor suppressor 2 S homeolog Protein, lzts2 Protein, LZTS2 Protein, lzts2a Protein, Lzts2 Protein, lzts2.S Protein

Hintergrund: The protein encoded by this gene belongs to the leucine zipper tumor suppressor family of proteins, which function in transcription regulation and cell cycle control. This family member can repress beta-catenin-mediated transcriptional activation and is a negative regulator of the Wnt signaling pathway. It negatively regulates microtubule severing at centrosomes, and is necessary for central spindle formation and cytokinesis completion. It is implicated in cancer, where it may inhibit cell proliferation and decrease susceptibility to tumor development. Alternative splicing of this gene results in multiple transcript variants.

Molekulargewicht: 72.6 kDa

NCBI Accession: NP_115805