ATP2A1/SERCA1 Protein (ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1) (Transcript Variant A) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2715042

Produktdetails

Target: ATP2A1/SERCA1 (ATP2A1) (ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant A

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ATP2A1/SERCA1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human ATP2A1 / SERCA1 (transcript variant a) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: ATP2A1/SERCA1 (ATP2A1) (ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1))

Andere Bezeichnung: Atp2a1,serca1 (ATP2A1 Produkte)

Synonyme: cb279, serca, serca1, wu:cegs655, wu:fb17h11, wu:fb19b10, zgc:92110, ATP2A1, atp2a, atp2a2, atp2b, ca-p60a, dar, serca2, SERCA1, ATP2A3, SERCA1a, Serca1, ATP2A, ATPase, Ca++ transporting, cardiac muscle, fast twitch 1, ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 S homeolog, atp2a1, ATP2A1, atp2a2.S, Atp2a1

Hintergrund: This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.

Molekulargewicht: 110.1 kDa

NCBI Accession: NP_775293

Pathways: Ribonucleoside Biosynthetic Process