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Apoptosis Inhibitor 5 Protein (API5) (Transcript Variant 3) (Myc-DYKDDDDK Tag)

API5 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2714802
$1,112.40
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
20 μg
Lieferung in 11 Werktagen
  • Target Alle Apoptosis Inhibitor 5 (API5) Proteine anzeigen
    Apoptosis Inhibitor 5 (API5)
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 3
    Spezies
    • 3
    • 1
    Human
    Quelle
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Apoptosis Inhibitor 5 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human API5 / MIG8 (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Apoptosis Inhibitor 5 (API5)
    Andere Bezeichnung
    Api5,mig8 (API5 Produkte)
    Synonyme
    api5l1, sr:nyz021, zgc:66211, wu:fb26c03, api5, API-5A, api5-A, MGC83290, API5, AAC-11, AAC11, AI196452, apoptosis inhibitor 5, apoptosis inhibitor 5 L homeolog, api5, api5.L, API5, Api5
    Hintergrund
    This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
    Molekulargewicht
    50.6 kDa
    NCBI Accession
    NP_001136403
    Pathways
    Growth Factor Binding
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