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PLAUR Protein (Plasminogen Activator, Urokinase Receptor) (Transcript Variant 2) (His tag)

PLAUR Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2713803
$429.00
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
10 μg
Lieferung in 16 Werktagen
  • Target Alle PLAUR Proteine anzeigen
    PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 2
    Spezies
    • 20
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Quelle
    • 15
    • 13
    • 3
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses PLAUR Protein ist gelabelt mit His tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human CD87 / uPAR (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin-Niveau
    < 0.1 EU per μg protein as determined by LAL test
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
    Andere Bezeichnung
    Cd87,upar (PLAUR Produkte)
    Synonyme
    Cd87, u-PAR, uPAR, CD87, U-PAR, UPAR, URKR, Par, Plaur3, uPAR-2, uPAR-3, PLAUR, plasminogen activator, urokinase receptor, Plaur, PLAUR
    Hintergrund
    This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
    Molekulargewicht
    32.6 kDa
    NCBI Accession
    NP_001005376
    Pathways
    Inositol Metabolic Process
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