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Protein C Receptor, Endothelial (PROCR) (AA 18-209) protein (Fc Tag) Protein

PROCR Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Produktnummer ABIN2181665
$319.00
Zzgl. Versandkosten $45.00
Lieferung in 2 bis 3 Werktagen
  • Target Alle PROCR Proteine anzeigen
    PROCR
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 18-209
    Spezies
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    Human
    Quelle
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses PROCR Protein ist gelabelt mit Fc Tag.
    Sequenz
    AA 18-209
    Produktmerkmale
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 48.6 kDa. As a result of glycosylation, the protein migrates as 65 kDa under reducing (R) condition, and 125 kDa under non-reducing (NR) condition (SDS-PAGE).
    Reinheit
    >95 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    50 mM Tris, 100 mM Glycine, pH 7.5
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    PROCR
    Andere Bezeichnung
    PROCR (PROCR Produkte)
    Synonyme
    PROCR, CCCA, CCD41, EPCR, AI325044, Ccca, Ccd41, Epcr, protein C receptor, protein C receptor, endothelial, PROCR, Procr
    Hintergrund
    Endothelial protein C receptor (PROCR) is also known as Activated protein C receptor (APC receptor), Endothelial cell protein C receptor, CD antigen CD201. PROCR / EPCR / CD201 is a N-glycosylated protein, with a soluble form exists. PROCR is probably released by a metalloprotease. PROCR seems to have the same activity as the membrane-bound form. PROCR / EPCR / CD201 is expressed strongly in the endothelial cells of arteries and veins in heart and lung. PROCR binds activated protein C and enhances protein C activation by the thrombin - thrombomodulin complex. PROCR plays a role in the protein C pathway controlling blood coagulation.
    Molekulargewicht
    48.6 kDa
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