Bone Morphogenetic Protein Receptor 1A (BMPR1A) (AA 24-152) protein (Fc Tag)

Produktnummer ABIN2180583

Produktdetails

Target: BMPR1A

Protein-Typ: Recombinant

Proteineigenschaft: AA 24-152

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses BMPR1A Protein ist gelabelt mit Fc Tag.

Sequenz: AA 24-152

Produktmerkmale: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 42 kDa. The protein migrates as 56 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Reinheit: >98 % as determined by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 50 mM Tris, 100 mM Glycine, pH 7.5

Handhabung: Please avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: No activity loss was observed after storage at: 4-8°C for 1 year in lyophilized state 4-8°C for 1 month under sterile conditions after reconstitution -20°C to -70°C for 3 months under sterile conditions after reconstitution

Antigendetails

Target: BMPR1A

Andere Bezeichnung: BMPR-IA (BMPR1A Produkte)

Synonyme: 10q23del, ACVRLK3, ALK3, CD292, SKR5, 1110037I22Rik, AU045487, BMPR-IA, Bmpr, BMPR-1, BRK-1, BMPR1A, acvrlk3, alk-3, alk3, cd292, skr5, BR1a, alk3tr, bmpr1a, zgc:136731, bone morphogenetic protein receptor type 1A, bone morphogenetic protein receptor, type 1A, bone morphogenetic protein receptor type 1A S homeolog, bone morphogenetic protein receptor, type IAa, BMPR1A, Bmpr1a, bmpr1a, bmpr1a.S, bmpr1aa

Hintergrund: The bone morphogenetic protein receptor, type IA is also known as BMPR1A or ALK3 is a protein which in humans is encoded by the BMPR1A gene. BMPR1A has also been designated as CD292 (cluster of differentiation 290). The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A (this protein) and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2[1]. Alk3-mediated BMP signaling in AV endocardial/mesenchymal cells plays a central role during cushion morphogenesis.

Molekulargewicht: 40.3 kDa

Pathways: Stem Cell Maintenance