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SIRPG Protein (Signal-Regulatory Protein gamma) (AA 29-360) (Fc Tag)

SIRPG Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN1692273
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  • Target Alle SIRPG Proteine anzeigen
    SIRPG (Signal-Regulatory Protein gamma (SIRPG))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 29-360
    Spezies
    Human
    Quelle
    • 4
    • 3
    • 2
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses SIRPG Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Recombinant Human Signal-Regulatory Protein γ/SIRPG/CD172g (C-Fc)
    Sequenz
    EEELQMIQPE KLLLVTVGKT ATLHCTVTSL LPVGPVLWFR GVGPGRELIY NQKEGHFPRV TTVSDLTKRN NMDFSIRISS ITPADVGTYY CVKFRKGSPE NVEFKSGPGT EMALGAKPSA PVVLGPAART TPEHTVSFTC ESHGFSPRDI TLKWFKNGNE LSDFQTNVDP TGQSVAYSIR STARVVLDPW DVRSQVICEV AHVTLQGDPL RGTANLSEAI RVPPTLEVTQ QPMRVGNQVN VTCQVRKFYP QSLQLTWSEN GNVCQRETAS TLTENKDGTY NWTSWFLVNI SDQRDDVVLT CQVKHDGQLA VSKRLALEVT VHQKDQSSDA TPVDDIEGRM DEPKSCDKTH TCPPCPAPEL LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSHEDPEVK FNWYVDGVEV HNAKTKPREE QYNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKALPAPIEK TISKAKGQPR EPQVYTLPPS REEMTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT PPVLDSDGSF FLYSKLTVDK SRWQQGNVFS CSVMHEALHN HYTQKSLSLS PGK
    Produktmerkmale
    Recombinant Human Signal-Regulatory Protein Gamma/SIRPG is produced with our HEK293 expression system. The target protein is expressed with sequence (Glu29-Pro360) of Human SIRPG fused with a FC tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Handhabung
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Lagerung
    4 °C/-20 °C/-80 °C
    Informationen zur Lagerung
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Haltbarkeit
    3 months
  • Target
    SIRPG (Signal-Regulatory Protein gamma (SIRPG))
    Andere Bezeichnung
    SIRPG (SIRPG Produkte)
    Synonyme
    CD172g, SIRP-B2, SIRPB2, SIRPgamma, bA77C3.1, SIRPG, signal regulatory protein gamma, signal-regulatory protein gamma, SIRPG, LOC716034, LOC102138723
    Sub Type
    Fusionprotein
    Hintergrund
    Signal-Regulatory Protein Gamma (SIRPG) is a member of the signal-regulatory protein (SIRP) family and also belongs to the immunoglobulin superfamily. SIRPG is detected in the liver, and at very low levels in the brain, heart, lung, pancreas, kidney, placenta, and skeletal muscle. SIRPG is an immunoglobulin-like cell surface receptor. On binding with CD47, SIRPG mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. SIRPG as receptor-type transmembrane glycoproteins is involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes.
    Alternative Names: Signal-Regulatory Protein Gamma, SIRP-Gamma, CD172 Antigen-Like Family Member B, Signal-Fegulatory Protein Beta-2, SIRP-b2, SIRP-Beta-2, CD172g, SIRPG, SIRPB2
    Molekulargewicht
    63.9kDa
    UniProt
    Q9P1W8
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