DLK1 Protein (AA 1-303) (DYKDDDDK Tag)
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- Target Alle DLK1 Proteine anzeigen
- DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-303
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses DLK1 Protein ist gelabelt mit DYKDDDDK Tag.
- Applikation
- SDS-PAGE (SDS)
- Verwendungszweck
- DLK1 (human) (rec.)
- Kreuzreaktivität
- Human
- Produktmerkmale
- Signal peptide and extracellular domain of human DLK1 (aa 1-303) are fused at the C-terminus to a FLAG®-tag.
- Reinheit
- >90 % (SDS-PAGE)
- Endotoxin-Niveau
- <0.1EU/μg purified protein (LAL test).
- Top Product
- Discover our top product DLK1 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Contains PBS.
- Handhabung
- After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. PBS containing at least 0.1 % BSA should be used for further dilutions.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
- Haltbarkeit
- 6 months
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- Target
- DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
- Andere Bezeichnung
- DLK1 (DLK1 Produkte)
- Hintergrund
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Protein Delta Homolog 1, Fetal Antigen 1, Preadipocyte Factor 1, Pref-1, FA1
The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.
- Molekulargewicht
- ~40kDa (SDS-PAGE)
- UniProt
- P80370
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