Nucleoporin 155kDa (NUP155) (N-Term) Peptid
NUP155
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN981037
Kurzübersicht für Nucleoporin 155kDa (NUP155) (N-Term) Peptid (ABIN981037)
Target
NUP155
(Nucleoporin 155kDa (NUP155))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- CCVMRYTTAG QLWNIISPRE FVDFSYTVGY KEGLLSCGIS LDWDEKRPEF
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-NUP155 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NUP155 (Nucleoporin 155kDa (NUP155))
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Hintergrund
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Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1, MIM 184756) and by liver X receptors (e.g., LXRA, MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR, MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).
Alias Symbols: KIAA0791, N155
Protein Size: 205 -
Molekulargewicht
- 23 kDa
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Gen-ID
- 9631
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NCBI Accession
- NM_004298, NP_004289
Target
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