Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) Peptid

Details zu Produkt Nr. ABIN980928
Proteinname
  • nr41/42/43
  • Nr4a2
  • nurr1
  • not
  • rnr1
  • hzf-3
  • tinur
  • NGFI-B
  • HZF-3
  • NOT
  • NURR1
  • RNR1
  • TINUR
  • Nurr1
  • RNR-1
  • TINOR
  • ngf1b
  • nr4a2
  • zgc:92696
  • nuclear receptor subfamily 4 group A member 2
  • nuclear receptor
  • nuclear receptor subfamily 4, group A, member 2
  • nuclear receptor subfamily 4, group A, member 2b
  • NR4A2
  • nr41/42/43
  • nr4a2
  • Nr4a2
  • nr4a2b
Spezies
Human
3
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
Optionen
Geblockter Antikörper anti-NR4A2 Antikörper (Nuclear Receptor Subfamily 4, Group A, Member 2) (N-Term) (ABIN2780752)
Produktmerkmale This is a synthetic peptide designed for use in combination with anti-NR4A2 antibody (Catalog #: ARP38753_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Reinigung Purified
Proteinname
Hintergrund NR4A2 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. The protein may act as a transcription factor. Mutations in NR4A2 gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of NR4A2 gene may be associated with rheumatoid arthritis.This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Four transcript variants encoding four distinct isoforms have been identified for this gene. Additional alternate splice variants may exist, but their full length nature has not been determined.This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Alias Symbols: HZF-3, NOT, NURR1, RNR1, TINUR

Protein Interaction Partner: CREB1,CDKN1C,COPS5,PIAS4,RPS6KA1,RXRA,RXRB,RARA,RARB

Protein Size: 598
Molekulargewicht 66 kDa
Gen-ID 4929
NCBI Accession NM_006186, NP_006177
UniProt P43354
Applikations-hinweise Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.