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Histone Deacetylase 3 (HDAC3) (C-Term) Peptid

HDAC3 Reaktivität: Ratte Wirt: Synthetic BP, WB
Produktnummer ABIN977905

Kurzübersicht für Histone Deacetylase 3 (HDAC3) (C-Term) Peptid (ABIN977905)

Target

HDAC3 (Histone Deacetylase 3 (HDAC3))

Spezies

Ratte

Quelle

  • 7
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequenz

    DVPADLLTYD RTDEADAEER GPEENYSRPE APNEFYDGDH DNDKESDVEI

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-Hdac3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    HDAC3 (Histone Deacetylase 3 (HDAC3))

    Hintergrund

    Hdac3 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Hdac3 is required to repress transcription of the POU1F1 transcription factor. Hdac3 acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation.

    Alias Symbols: Hdac3

    Protein Interaction Partner: Hr

    Protein Size: 428

    Molekulargewicht

    49 kDa

    Gen-ID

    84578

    NCBI Accession

    NM_053448, NP_445900

    UniProt

    Q6P6W3
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