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CD274 (PD-L1) (C-Term) Peptid

PD-L1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN974661
  • Target Alle PD-L1 Produkte
    PD-L1 (CD274 (PD-L1))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 6
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    ELIRDYNSSR EDSLQDAWDY VQAQVKCCGW VSFYNWTDNA ELMNRPEVTY
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-CD82 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PD-L1 (CD274 (PD-L1))
    Hintergrund
    This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

    Alias Symbols: 4F9, C33, GR15, IA4, KAI1, R2, SAR2, ST6, TSPAN27

    Protein Interaction Partner: BCL3,CTNNB1,KAT5,MAP3K1,NCOR1,NFKB1,POLR2A,RUVBL1,RUVBL2,TAB2,CANX,CD19,CD4,CD63,EGFR,ERBB2,ERBB3,HBEGF,HLA-DMA,HLA-DMB,HLA-DRA,IGSF8,ITGA3,ITGA4,ITGA6,ITGB1,ITGB2,LRP1,NUP88,PTGFRN,VANGL1,CD151,CD19,CD4,CD46,CD63,CD9,EGFR,ERBB2,ERBB3,HBEGF,HLA-DMB,HLA-DO

    Protein Size: 242
    Molekulargewicht
    27 kDa
    Gen-ID
    3732
    NCBI Accession
    NM_001024844
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