BMI1 Polycomb Ring Finger Oncogene (BMI1) (Middle Region) Peptid

Details zu Produkt Nr. ABIN973837, Anbieter: Anmelden zum Anzeigen
Proteinname
  • FLVI2/BMI1
  • PCGF4
  • RNF51
  • AW546694
  • Bmi-1
  • Pcgf4
  • bmi1
  • pcgf4
  • psc1
  • wu:fb17g03
  • wu:fd18f06
  • BMI-1
  • bmi-1
  • bmi1-a
  • bmi1-b
  • bmi1b
  • rnf51
  • xbmi-1
  • BMI1 proto-oncogene, polycomb ring finger
  • BMI1 polycomb ring finger oncogene
  • Bmi1 polycomb ring finger oncogene
  • bmi1 polycomb ring finger oncogene 1a
  • COMMD3-BMI1 readthrough
  • BMI1 proto-oncogene, polycomb ring finger L homeolog
  • BMI1
  • LOC100230513
  • Bmi1
  • bmi1a
  • COMMD3-BMI1
  • bmi1.L
Protein Region
Middle Region
Spezies
Human, Maus
5
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Geblockter Antikörper anti-BMI1 Antikörper (BMI1 Polycomb Ring Finger Oncogene) (Middle Region) (ABIN2778059)
Sequenz MDIPNTFQID VMYEEEPLKD YYTLMDIAYI YTWRRNGPLP LKYRVRPTCK
Produktmerkmale This is a synthetic peptide designed for use in combination with anti-Bmi1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Reinigung Purified
Hintergrund Bmi1 is a component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

Alias Symbols: AW546694, Bmi-1, Pcgf4

Protein Interaction Partner: Phc2,Rnf2,CBX4,CBX8,Cbx2,Dmap1,Dnmt3b,HSPA4,Kdm2b,PHC1,PHC2,PHC3,Phc1,Phc3,RING1,Rnf2,SCMH1,SMARCA5,Slc11a1

Protein Size: 324
Molekulargewicht 37 kDa
Gen-ID 12151
NCBI Accession NM_007552, NP_031578
UniProt P25916
Forschungsgebiet Hematopoietic Progenitors, Cell Cycle, Transcription Factors, Cancer
Applikationshinweise Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.