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anti-alpha Adducin (ADD1) Antikörper

Bezeichnung:: anti-Adducin 1 (Alpha) Antikörper (ADD1)

Auf www.antikoerper-online.de finden Sie aktuell 188 Adducin 1 (Alpha) (ADD1) Antikörper von 25 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen alpha Adducin Proteine (8) und alpha Adducin Kits (2) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 209 alpha Adducin Produkte verfügbar.

Synonyme:: ADD1, add1-a, add2, adda, AI256389, alpha-adducin, bZ1H20.1, cb787, zgc:158352

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	ADD1	118	P35611
	ADD1	11518	Q9QYC0
	ADD1	24170	Q63028
Alle Spezies anzeigen Weitere Synonyme anzeigen

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anti-Human alpha Adducin Antikörper:

anti-Mouse (Murine) alpha Adducin Antikörper:

anti-Rat (Rattus) alpha Adducin Antikörper:

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Weitere Antikörper gegen alpha Adducin Interaktionspartner

Human Adducin 1 (Alpha) (ADD1) Interaktionspartner

These findings unveil a novel function of ADD1 in maintaining spindle pole integrity through its interaction with TPX2.
alpha-adducing SNPs were not associated with bone density among lead workers.
These findings highlight that ADD1 methylation may have a contributing role in the pathogenesis of EH with varying implications for both genders.
The ADD1 Gly460Trp gene polymorphism is significantly and independently associated with Essential Hypertension risk in a Caucasian population from Madeira Island.
ZNF322A overexpression transcriptionally dysregulates genes involved in cell growth and motility therefore contributes to lung tumorigenesis and poor prognosis
ADD1 rs4963 polymorphism showed an increased hypertension risk.
This indicates that ADD1 G460W polymorphism could be an important factor in the pathophysiology of tinnitus.
study shows that the a-adducin G460T polymorphism is associated with essential hypertension
Study shows that ADD1-rs4963 conferred susceptibility to colorectal cancer (CRC) suggesting an association between ADD1 and CRC risk.
The T allele of ADD1 is associated with essential hypertension in Asians.
study of potential effects of interaction between DNA methylation of ADD1 promoter and ADD1 tagSNPs and environmental factors on essential hypertension (EH); results indicate ADD1 SNP rs4961 has a protective role in development of EH; interactions between alcohol consumption and DNA methylation of ADD1 gene promoter have a significant role in modifying EH susceptibility
There were significant differences between the control group and pediatric hypertensive group in terms of ACE I/D (P<0.05) and AGT M235T (P<0.05) polymorphisms, but there were no differences in ADD Gly460Trp (P>0.05) polymorphism.
A significant association was found between ADD1 gene G614T polymorphism and essential hypertension in Chinese patients. Further studies need to be done to confirm these findings in a large sample.
When alpha-adducin complexes with sodium potassium ATPase in astrocytes, non-cell autonomous neurodegeneration is triggered.
Data indicate that adducin promotes adhesion by regulating desmosomes and is part of a protective pathway in pemphigus.
Phosphorylation of ADD1 at Ser12 and Ser355 by cyclin-dependent kinase 1 enables ADD1 to bind to myosin-X (Myo10).
Fnnctional polymorphism in the phosphorylation site of ADD1 (rs4963) may influence the susceptibility of non-cardia gastric cancer.
concentration of AST was inversely correlated with ADD1 CpG2-5 methylation levels in female controls. These observations may bring new hints to elaborate the pathogenesis of essential hypertension
study is the first meta-analysis to evaluate the influences of ACE and ADD1 polymorphisms on blood pressure responses to hydrochlorothiazide to combine the inconsistent results of previous studies
the rs4963 polymorphism within ADD1 gene is associated with essential hypertension in the Chinese population

Mouse (Murine) Adducin 1 (Alpha) (ADD1) Interaktionspartner

Sez6l2 is one of the auxiliary subunits of the AMPA receptor and acts as a scaffolding protein to link GluR1 to ADD. Furthermore, Sez6l2 overexpression upregulates ADD phosphorylation, whereas siRNA-mediated downregulation of Sez612 prevents ADD phosphorylation, suggesting that Sez6l2 modulates AMPA-ADD signal transduction.
Reduction in ADD1 protein in NEK1 mutant mice is associated with hyperphosphorylation of ADD1, thereby preventing the interaction with MYO10 during meiotic spindle formation
adducin activity is not essential for actin ring assembly and periodicity but is necessary to control the diameter of both actin rings and axons and actin filament growth within rings.
Targeted deletion of Add1 reveals strain-dependent hyperkyphosis and megaesophagus in c57bl, 129s1 and B6 mice.
organization of a spectrin-like cytoskeleton is associated with keratinocyte differentiation, and cytoskeleton disruption is mediated by either PKCdelta(Thr505) phosphorylation associated with phosphorylated adducin or due to reduction of endogenous adducin
These results strongly suggest coordinated expression and phosphorylation of alpha-, beta-, and gamma-adducins as key mechanism underlying synaptic plasticity, motor coordination performance and learning behaviors.
Reorganization of the unique cytoskeletal network defining a primary quiescent T cell is mediated thru the TCR-dependent modification & downregulation of alpha-adducin, resulting in a cytoskeletal shape compatible with T cell effector & memory functions.
Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice

alpha Adducin (ADD1) Antigen-Profil

Beschreibung des Gens

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms\; however, not all variants have been fully described.

Alternative names and synonyms associated with alpha Adducin (ADD1)

adducin 1 (ADD1) Antikörper
adducin 1 (alpha) (Add1) Antikörper
adducin 1 (Add1) Antikörper
adducin 1 (alpha) (add1) Antikörper
adducin 1 (add1) Antikörper
adducin 1 S homeolog (add1.S) Antikörper

ADD1 Antikörper
add1-a Antikörper
add2 Antikörper
adda Antikörper
AI256389 Antikörper
alpha-adducin Antikörper
bZ1H20.1 Antikörper
cb787 Antikörper
zgc:158352 Antikörper

Bezeichner auf Proteinebene für ADD1

alpha-adducin , erythrocyte adducin alpha subunit , erythrocyte adducin subunit alpha , alpha-ADD , adducin 1 (alpha) , alpha-adducin-like , adducin 2 (beta)

GENE ID	SPEZIES
118	Homo sapiens
11518	Mus musculus
24170	Rattus norvegicus
422882	Gallus gallus
507193	Bos taurus
555511	Danio rerio
100172752	Pongo abelii
100401343	Callithrix jacchus
100483493	Ailuropoda melanoleuca
448173	Xenopus (Silurana) tropicalis
394387	Xenopus laevis
488796	Canis lupus familiaris
700805	Macaca mulatta
740376	Pan troglodytes
100015485	Monodelphis domestica
100051451	Equus caballus
100220908	Taeniopygia guttata
100351048	Oryctolagus cuniculus
100541144	Meleagris gallopavo
100564853	Anolis carolinensis
100590491	Nomascus leucogenys
100517353	Sus scrofa
100713878	Cavia porcellus

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