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Human Polyclonal GC Primary Antibody für ELISA - ABIN2477106
Ho, Cheng, Lee, Liu, Lee, Wang, Wang: Novel biomarkers predict liver fibrosis in hepatitis C patients: alpha 2 macroglobulin, vitamin D binding protein and apolipoprotein AI. in Journal of biomedical science 2010
Human Polyclonal GC Primary Antibody für ELISA, WB - ABIN547998
Sandford, Paré: Genetic risk factors for chronic obstructive pulmonary disease. in Clinics in chest medicine 2001
Human Polyclonal GC Primary Antibody für ELISA, WB - ABIN263165
Vicente-Vicente, Ferreira, González-Buitrago, López-Hernández, López-Novoa, Morales: Increased urinary excretion of albumin, hemopexin, transferrin and VDBP correlates with chronic sensitization to gentamicin nephrotoxicity in rats. in Toxicology 2013
Show all 2 Pubmed References
This study directly measured serum free 25-hydroxyvitamin D (25(OH)D) and DBP in pregnant adolescents. Longitudinal increase in DBP was associated with modest decrease in free 25(OH)D.
VDR and VDBP mutations were found highly related with Obstructive sleep apnea syndrome.
GC SNPs rs4588 and rs7041 were not associated with asthma risk in a Tunisian population.
The rs7041 and rs4588 polymorphisms of the DBP gene and protein level were measured in 136 COPD and 68 non-COPD Thai males. In the COPD group, GC1-1 gave increased forced expiratory volume at 1 s % predicted compared with GC1-2 but with no significant difference. Significantly lower average DBP serum levels were observed in COPD than non-COPD subjects. Positive correlation between serum DBP and forced expiratory volume
Women with polycystic ovary syndrome (PCOS) had lower DBP, but similar bioavailable or free 25(OH)D concentrations compared to controls, independent of BMI and age. DBP was not associated with insulin resistance or BMI in PCOS. Further studies are needed to investigate the pathophysiology and clinical implications of reduced DBP in PCOS.
Group-specific Component (GC) variants could be implicated in childhood bronchial asthma pathogenesis.
A significant interaction was observed between High protein/Low fat diet and the rs7041 polymorphism in the moderate- and severe-depression groups.
The meta-analysis identified associations for one intron GC variant [rs843010:1.4 (1.1, 1.9) P < 0.05] and two variants of the flanking region of GC [rs842991:1.5 (1.1, 2.0) P < 0.05; rs16846876:0.75 (0.58, 0.98) P < 0.05] and risk of preeclampsia
we investigated whether polymorphisms within the vitamin D receptor (VDR) ,1,25-dihydroxyvitamin D 24-hydroxylase (CYP24A1) , cytochrome P450 monooxygenase 25(OH)D-1alpha-hydroxylase (CYP27B1) and GC (encoding the vitamin D binding protein (VDBP)) (1296) genes could play a role in DFX pharmacokinetics
VDBP in the cervicovaginal fluid (CVF) independently predicts intra-amniotic infection and imminent preterm delivery in women with PTL, whereas in women with preterm premature rupture of membranes, an elevated VDBP level in CVF is not associated with increased risks of these two outcome variables.
SNPs of the VDR and GC genes are associated with vitamin D deficiency in postmenopausal Mexican women.
GC rs7041 genotype modified the effects of pregnancy on maternal and placental vitamin D metabolism.
Urinary VDBP correlated with proteinuria and renal SLE disease activity index, and predicted the development of proteinuria in lupus nephritis.
Findings implied that VDBP rs7041-G and rs3733359-T variants may contribute to increased susceptibility to HCV infection in a high-risk Chinese population.
Polymorphisms of VDBP rs4588 and rs2282679 may play a potentially important role in epilepsy susceptibility.
The study findings suggested a possible clinical application of uVDPB as an early and a good marker for the detection of early renal disease in type 2 diabetes mellitus Saudi patients.
GC gene variant has no effect on 25-hydroxyvitamin D levels.
genetic association study in population in north India: Data suggest (1) GT allele of VDBP SNP rs7041, (2) VDBP allelic combination (GC1F/1F: T allele rs4588; C allele rs7041), and (3) GA allele of CYP2R1 SNP rs2060793 are associated with vitamin D deficiency in women with PCOS (polycystic ovarian syndrome) in population studied. (VDBP = vitamin D-binding protein; CYP2R1 = cytochrome P450 family 2 subfamily R member 1)
The A allele of VDBP gene polymorphism might be a potential risk factor for progression of chronic urticarial.
The present study indicates an association between VDR and vitamin D binding protein Single Nucleotide Polymorphisms and Type 1 Diabetes Mellitus among Turkish subjects.
Associations between SNPs and the studied traits were strongest for SNPs that were located within and immediately upstream of the group-specific component (GC) gene. Our results suggest GC as the gene that underlies the QTL for clinical mastitis and milk production.
the levels of trisialylated triantennary glycans of haptoglobin and vitamin D-binding protein increased significantly as liver cancer disease progressed, while the alteration in these protein levels were modest.
results show DBP is a significant chemotactic cofactor in vivo and not specific for C5a, suggesting that this ubiquitous plasma protein may have a more significant role in neutrophil recruitment than previously recognized
Effects of estradiol on the endocytic transport of vitamin D carrier protein in hepatocytes.
Data suggest that whereas DBP is important to total circulating 1,25(OH)(2)D(3) and sequesters extracellular levels of this hormone both in vivo and in vitro, the binding protein does not influence the hormone's biologically active pool.
The aim of this research was to screen polymorphism and to perform association study of porcine AMBP, GC and PPP1R3B genes with meat quality traits.
The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, vitamin D-binding alpha-globulin
, vitamin D-binding protein
, group-specific component (vitamin D binding protein)
, vitamin D binding protein
, group-specific component
, vitamin-D binding protein
, group-specific component (vitamin D binding protein) S homeolog