Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Weitere Synonyme anzeigen
Wählen Sie die gewünschte Spezies
Results showed that STMN1 overexpression was significantly associated with lymphatic metastatic recurrence in pN0 esophageal squamous cell carcinoma (ESCC) patients. STMN1 levels are regulated by the PI3K (zeige PIK3CA Proteine) pathway, and STMN1 can act as a surrogate marker of PI3K (zeige PIK3CA Proteine) pathway signaling related to tumor recurrence.
The investigation confirmed that stathmin expression was correlated with more aggressive behavior of cervical cancer.
High STMN1 Expression is Associated with Cancer Progression and Chemo-Resistance in Lung Squamous Cell Carcinoma.
STMN1 expression was significantly associated with prognosis and tumour differentiation in ESCC, indicating that STMN1 expression is an independent prognostic factor for ESCC and could be a potential biomarker. Regulating the expression of STMN1 could influence tumour cell motility, invasion and proliferation
T3-mediated suppression of STMN1 supports the theory that T3 plays an inhibitory role in HCC (zeige FAM126A Proteine) tumor growth, and suggests that the lack of normal THR (zeige TRH Proteine) function leads to elevated STMN1 expression and malignant growth
These results suggest that stathmin acts as an oncogene (zeige RAB1A Proteine) and is transcriptionally regulated by mutant p53 (zeige TP53 Proteine), but not by wild-type p53 (zeige TP53 Proteine). Stathmin could be a potential anti-tumor therapeutic target in oral squamous cell carcinoma
Results suggest that Stathmin 1 (STMN1) plays an important role in cell proliferation and migration.
STMN1 expression was higher in basal-type cell lines than in luminal-type cell lines, and overall survival and post-progression survival in the high STMN1 expression breast cancer patients were shorter than in low STMN1 expression patients. High STMN1 expression is a possible marker of breast cancer aggressiveness in association with proliferation, phenotype and cancer stem cell type
we found upregulated expression of STMN1 in the atypical/anaplastic meningioma group, relative to that in the benign meningioma group. STMN1, therefore, is a promising target to improve cure rates in meningioma cases.
An increased risk of sporadic atypical meningioma recurrence can be found in cases with elevated expression of STMN1.
These findings suggest that during embryo implantation, knockdown of Stmn1 suppresses decidualisation by inhibiting the expression of p-Akt (zeige AKT1 Proteine), HIF-1alpha (zeige HIF1A Proteine) and VEGF (zeige VEGFA Proteine), thus leading to impaired embryo implantation.
The data suggest that STMN1 mediates the progesterone production by modulating the promoter activity of Star and Cyp11a1 (zeige CYP11A1 Proteine).
EGFR (zeige EGFR Proteine) suppression of mitotic regulators including Rcc2 (zeige RCC2 Proteine) and Stathmin 1 are a mechanism for catagen induction in mouse skin
We identified stathmin as a key molecule aiding in septin (zeige SEPT6 Proteine)-independent cytokinesis, demonstrated that stathmin supplementation is sufficient to override cytokinesis failure in SEPT7 (zeige SEPT7 Proteine)-null fibroblasts
Overexpressing stathmin reduces complement receptor 3 (zeige ITGAM Proteine)-mediated phagocytosis and cellular activation, implicating a pivotal inhibitory role for stathmin in classically activated macrophages.
Stathmin cooperates with p27(kip1 (zeige CDKN1B Proteine)) to control the early phase of G1 to S phase transition and that this function may be of particular relevance in the context of tumor progression.
The protein profiles during murine embryo implantation were clarified. Stathmin 1 might be a potential regulator of embryo implantation.
Results show an important role for stathmin during adult neurogenesis in the subgranular zone of the mouse hippocampus; propose that stathmin controls the transition from neuronal precursors to early postmitotic neurons
Stathmin mutations disrupt changes in microtubule stability, GluA2 (zeige GRIA2 Proteine) localization, synaptic plasticity and memory.
Stmn deletion does not prolong the lifespan of spinal muscular atrophy-like mice, suggesting that stathmin dysregulation and microtubule disruption are not a cause but rather a consequence of SMA (zeige SMN1 Proteine) pathology.
Op18 reveals the contribution of nonkinetochore microtubules to the dynamic organization of the vertebrate meiotic spindle.
This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene.
leukemia-associated phosphoprotein p18
, oncoprotein 18
, phosphoprotein 19
, phosphoprotein p19
, stathmin 1/oncoprotein 18
, transmembrane protein C1orf215
, leukemia associated phosphoprotein p18
, leukemia-associated gene protein
, leukemia-associated cytosolic phosphoprotein stathmin
, stathmin 1 a
, stathmin 1/oncoprotein 18b
, stathmin 1
, stathmin 1 b
, stathmin 1b
, stathmin clone XO35