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anti-Human CNTF Receptor alpha Antikörper:
anti-Rat (Rattus) CNTF Receptor alpha Antikörper:
anti-Mouse (Murine) CNTF Receptor alpha Antikörper:
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Human Monoclonal CNTF Receptor alpha Primary Antibody für WB - ABIN967632
Krüttgen, Grötzinger, Kurapkat, Weis, Simon, Thier, Schröder, Heinrich, Wollmer, Comeau: Human ciliary neurotrophic factor: a structure-function analysis. in The Biochemical journal 1995
Mouse (Murine) Polyclonal CNTF Receptor alpha Primary Antibody für ELISA, WB - ABIN188694
Yokota, Yoshikawa, Hirabayashi, Nakase, Uranishi, Nishimura, Sugie, Ishizaka, Sakaki: Expression of ciliary neurotrophic factor (CNTF), CNTF receptor alpha (CNTFR-alpha) following experimental intracerebral hemorrhage in rats. in Neuroscience letters 2005
Human Polyclonal CNTF Receptor alpha Primary Antibody für IF (p), IHC (p) - ABIN687637
Schwieger, Warnecke, Lenarz, Esser, Scheper: Neuronal Survival, Morphology and Outgrowth of Spiral Ganglion Neurons Using a Defined Growth Factor Combination. in PLoS ONE 2015
The family-based study showed no association between the CNTFR rs7036351, NET rs3785143 polymorphisms, and attention-deficit hyperactivity disorder.
R28E mutation in CNTF (zeige CNTF Antikörper) abrogatesIL-6 receptor-dependent but retains CNTF (zeige CNTF Antikörper) receptor-dependent signaling via glycoprotein 130/ LIFR (zeige LIFR Antikörper).
gene expression and surface expression in NK92 cells of ciliary neurotrophic factor alpha (CNTFR-alpha) and glycoprotein (gp)130 in natural killer (NK) cells, in the context of malaria, were investigated.
Data indicate that CNTFRalpha plays a role in the formation or maintenance of tumor-initiating cells in gliomas, is a marker that correlates with histological grade, may underlie treatment resistance in some cases, and is a potential therapeutic target.
expression of neurotrophin (zeige BDNF Antikörper) receptors Pan (zeige SUPT6H Antikörper)-Trk (zeige NTRK1 Antikörper), p75 neurotrophin receptor (p75 (zeige NGFR Antikörper)(NTR (zeige NGFR Antikörper)) and ciliary neurotrophic factor receptor-alpha in ulveal melanoma does not show a role in growth.
Data show that variants in CNTFR were significantly associated with a lower age at onset of the eating disorders.
interactions of CNTFR with LIFR and gp130 in vitro
C174T polymorphism in exon 9 of CNTFR is significantly associated with fat-free (zeige VPS51 Antikörper) mass in men and women, with concomitant differences in muscular strength.
Structural and docking interaction studies showed that the R197L substitution destabilized the contact site between CLC (zeige CLC Antikörper) and CNTFRalpha.
In liver CNTFRalpha serves as a key modulator in regulating PI3K and AMP-activated protein kinase dynamically under CNTF stimulation, resulting in the increase of glucose uptake and translocation of glucose transporter 4.
Study proposes a novel insight that miR (zeige MLXIP Antikörper)-696 down-regulates C2C12 cell myogenesis by inhibiting CNTFRalpha expression.
The data, along with previous work indicating no effect of muscle specific (zeige EIF3K Antikörper) ciliary neurotrophic factor (zeige CNTF Antikörper) alpha (CNTFRalpha) depletion on motor innervation, suggest that motor neuron and muscle CNTFRalpha function in concert to maintain motor neuron axons.
CNTFR expression was downregulated by androgen in the inguinoscrotal fat pad suggesting that the genitofemoral nerve may be masculinised to control gubernacular migration in the inguinoscrotal phase of testicular descent by a negative regulating mechanism in mouse embryos .
The data of this study data suggest that CNTF (zeige CNTF Antikörper) receptors may promote adult motor neuron survival.
CNTF (zeige CNTF Antikörper)-Ralpha and CNTF (zeige CNTF Antikörper) are present in the pre-and post-synaptic sites of the neuromuscular junction.
Data show that CNTF receptor alpha subunit (zeige POLG Antikörper), CNTFRalpha, signaling in leptin (zeige LEP Antikörper)-responsive neurons is not required for endogenous maintenance of energy balance.
identification of neuropoietin as a new ligand with with important implications for murine nervous system development
CNTF (zeige CNTF Antikörper)-CNTFRalpha activates the JAK (zeige JAK3 Antikörper)/STAT (zeige STAT1 Antikörper) pathway leading to enhanced Cx43 (zeige GJA1 Antikörper) expression and intercellular coupling
It is suggested that the loss of CNTFRalpha from axons renders RGCs unresponsive to CNTF (zeige CNTF Antikörper), thereby contributing to regenerative failure and death, while its appearance on glia may promote glial scarring.
Co-administration of ciliary neurotrophic factor (zeige CNTF Antikörper) with its soluble receptor (zeige IFNAR1 Antikörper) protects against neuronal death and enhances neurite outgrowth.
This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.
CNTF receptor subunit alpha
, ciliary neurotrophic factor receptor subunit alpha
, CNTFR alpha
, ciliary neurotrophic factor receptor alpha
, ciliary neurotrophic factor receptor subunit alpha preproprotein
, GPA receptor subunit alpha
, growth promoting activity (GPA) receptor alpha; GPARalpha
, growth-promoting activity receptor subunit alpha
, ciliary neurotrophic factor receptor
, ciliary neurotrophic factor receptor subunit alpha-like