Ratte IgG2a, kappa Isotyp-Kontrolle

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Klonalität (Klon)
Monoklonal ()
Activation (Act), Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Isotype Control (IsoC), Western Blotting (WB)
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Hersteller Produkt- Nr.
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Klon RTK2758
Isotyp IgG2a kappa
Produktmerkmale The RTK2758 immunoglobulin reacts with KLH. The isotype of this antibody is rat IgG2a, κ. This antibody was chosen as an isotype control after screening on a variety of resting, activated, live, and fixed mouse, rat and human tissues.
Reinigung The immunoglobulin was purified by affinity chromatography, and conjugated with PerCP under optimal conditions. The solution is free of unconjugated PerCP and unconjugated immunoglobulin.
Andere Bezeichnung IgG2a kappa
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 0.2 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Protect from prolonged exposure to light. Do not freeze.
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C.
Allgemeine Veröffentlichungen Benhamron, Pattanayak, Berger, Tirosh: "mTOR activation promotes plasma cell differentiation and bypasses XBP-1 for immunoglobulin secretion." in: Molecular and cellular biology, Vol. 35, Issue 1, pp. 153-66, 2014 (PubMed).

Seach, Ueno, Fletcher, Lowen, Mattesich, Engwerda, Scott, Ware, Chidgey, Gray, Boyd: "The lymphotoxin pathway regulates Aire-independent expression of ectopic genes and chemokines in thymic stromal cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 8, pp. 5384-92, 2008 (PubMed).

Nishimoto, Lee, Hong, Potter, Maeda-Yamamoto, Kinoshita, Kawakami, Mittler, Kwon, Ware, Croft, Kawakami: "Costimulation of mast cells by 4-1BB, a member of the tumor necrosis factor receptor superfamily, with the high-affinity IgE receptor." in: Blood, Vol. 106, Issue 13, pp. 4241-8, 2005 (PubMed).

Jiang, Lagenaur, Narayanan: "Integrin-associated protein is a ligand for the P84 neural adhesion molecule." in: The Journal of biological chemistry, Vol. 274, Issue 2, pp. 559-62, 1999 (PubMed).