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Taken together, these results provide new insights into the mechanism of action of LCoR (zeige Lcor ELISA Kits) and RIP140 and highlight their strong interplay for the control of gene expression and cell proliferation in breast cancer cells.
Study found low expression level of RIP140 in tumor-associated macrophages (TAM (zeige CCNA1 ELISA Kits)) of hepatocellular carcinoma (HCC (zeige FAM126A ELISA Kits)) tissues and demonstrated that RIP140 expression in plays a role in the growth of hepatoma cells.
results indicated that there was a significant association between migraine and gene-gene interaction among the CYP19A1 (zeige CYP19A1 ELISA Kits), FSHR (zeige FSHR ELISA Kits), ESR1 (zeige ESR1 ELISA Kits) and NRIP1.
Data indicate that nuclear receptor interacting protein 1 (NRIP1) is elevated in tumors compared to cancer adjacent normal tissue.
NOP14 (zeige Nop14 ELISA Kits) suppresses breast cancer progression by inhibiting NRIP1/Wnt (zeige WNT2 ELISA Kits)/beta-catenin (zeige CTNNB1 ELISA Kits) pathway.
NRIP1 contributes to the mitochondrial dysfunction observed in DS. Furthermore, they suggest that the NRIP1-PGC-1alpha (zeige PPARGC1A ELISA Kits) axe might represent a potential therapeutic target for restoring altered mitochondrial function in DS.
RIP140 gene has been shown to be involved in the regulation of energy expenditure, in mammary gland development and intestinal homeostasis as well as in behavior and cognition
Downregulation of RIP140 promoted the tumorigenicity of HCC (zeige FAM126A ELISA Kits) cells in vitro.
Data suggest that vitamin D receptor target genes (NRIP1; DUSP10, dual specificity phosphatase 10; THBD, thrombomodulin; TRAK1, trafficking protein kinesin binding 1) can be used as markers for individual's response to vitamin D3 supplements.
RIP140 negatively regulated the macrophage expression of ATP-binding cassette transporters A1 and G1.
It is able to modulate the transcription of certain genes involved in AD pathology, such as b-APP (zeige APP ELISA Kits) cleaving enzyme (BACE1 (zeige BACE ELISA Kits)) and GSK3 (zeige GSK3b ELISA Kits). Consequently, we found that RIP140 overexpression reduced the generation of Ab in a neuroblastoma (zeige ARHGEF16 ELISA Kits) cell line by decreasing the transcription of b-APP (zeige APP ELISA Kits) cleaving enzyme via a PPARge dependent mechanism.
These data indicate that dominant NRIP1 mutations can cause kidney and urinary tract by interference with retinoic acid transcriptional signaling, shedding light on the well documented association between abnormal vitamin A levels and renal malformations in humans, and suggest a possible gene-environment pathomechanism in this disease
RIP140 has a unique role in the acute effect of beta-3 adrenergic receptor (zeige ADRB3 ELISA Kits) activation.
depletion of receptor-interacting protein 140 could significantly alleviate the inhibitory effects of estrogen on osteoclasts formation and bone resorption activity.
RIP140 protects LSD1's catalytic domain and antagonizes its Jade-2-mediated ubiquitination and degradation.
Nuclear receptor interacting protein 140 (RIP140) is an identified nuclear receptor corepressor that has been shown to suppress mitochondrial biogenesis in skeletal muscle.
Data show that 7,12-dimethylbenzanthracene (DMBA)-induced carcinogenesis is suppressed in nuclear receptor interacting protein 1 (Nrip1) knockout mice.
RIP140 plays an important role in maintaining brain cholesterol homeostasis through, partially, regulating cholesterol metabolism in, and mobilization from, astrocyte.
RIP140 translocation to the cytoplasm is an early response to ER stress and provides protection against neuronal death.
Study revealed an emotional regulatory function of macrophage-derived RIP140 in the VMH, and secondary dysregulation of NPY (zeige NPY ELISA Kits) within hypothalamic astrocyte population, which might be associated with the observed behavioral phenotype of MPhiRIPKD mice.
Nuclear receptor interacting protein 1 (NRIP1) is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors. Also known as RIP140, this protein modulates transcriptional activity of the estrogen receptor.
nuclear receptor interacting protein 1
, nuclear receptor-interacting protein 1-like
, nuclear factor RIP140
, nuclear receptor-interacting protein 1
, receptor interacting protein 140
, receptor-interacting protein 140