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Mouse (Murine) PLAUR Protein expressed in Human Cells - ABIN2007425
Dear, Medcalf: The urokinase-type-plasminogen-activator receptor (CD87) is a pleiotropic molecule. in European journal of biochemistry / FEBS 1998
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Human PLAUR Protein expressed in HEK-293 Cells - ABIN2713801
Ge, Siegel, Jordan, Naumann: Ligand binding alters dimerization and sequestering of urokinase receptors in raft-mimicking lipid mixtures. in Biophysical journal 2014
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
urokinase plasminogen activator surface receptor
, plasminogen activator, urokinase receptor
, urokinase plasminogen activator receptor
, urokinase-type plasminogen activator receptor
, monocyte activation antigen Mo3
, u-plasminogen activator receptor form 2
, urokinase-type plasminogen activator (uPA) receptor
, plasminogen activator urokinase receptor 3
, urinary plasminogen activator receptor 2
, urinary plasminogen activator receptor 3