anti-Biglycan (BGN) Antikörper

Bezeichnung:: anti-Biglycan Antikörper (BGN)

Auf www.antikoerper-online.de finden Sie aktuell 129 Biglycan (BGN) Antikörper von 21 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Biglycan Kits (46) und Biglycan Proteine (31) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 215 Biglycan Produkte verfügbar.

Synonyme:: BG, BGN, BSPG1, DKFZp468I2427, dspg1, pg-s1, PGI, slrr1a, xbgn, zgc:77123, zgc:91989

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	BGN	633	P21810
	BGN	12111	P28653
	BGN	25181	P47853
Alle Spezies anzeigen Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-Biglycan (BGN) Antikörper

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anti-Human Biglycan Antikörper:

anti-Mouse (Murine) Biglycan Antikörper:

anti-Rat (Rattus) Biglycan Antikörper:

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Verknüpfte Pathways mit anti-Biglycan Antikörper

Glycosaminoglycan Metabolic Process

Weitere Produktkategorien zu Biglycan Antikörper

Am meisten referenzierte anti-Biglycan Antikörper

Human Polyclonal Biglycan Primary Antibody für IHC, ELISA - ABIN188683 : Antipova, Orgel: Non-enzymatic decomposition of collagen fibers by a biglycan antibody and a plausible mechanism for rheumatoid arthritis. in PLoS ONE 2012 (PubMed)
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Human Polyclonal Biglycan Primary Antibody für IF (p), IHC (p) - ABIN872817 : Huang, Zou, Shi, Zhang, Pen, Zhang, Gao, Wang: The effect of electroacupuncture on the extracellular matrix synthesis and degradation in a rabbit model of disc degeneration. in Evidence-based complementary and alternative medicine : eCAM 2014 (PubMed)
Show all 2 Pubmed References
Human Polyclonal Biglycan Primary Antibody für IHC, IHC (p) - ABIN4284625 : Van Bockstal, Lambein, Van Gele, De Vlieghere, Limame, Braems, Van den Broecke, Cocquyt, Denys, Bracke, Libbrecht, De Wever: Differential regulation of extracellular matrix protein expression in carcinoma-associated fibroblasts by TGF-β1 regulates cancer cell spreading but not adhesion. in Oncoscience 2015 (PubMed)
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Human Polyclonal Biglycan Primary Antibody für WB - ABIN513714 : Gasimli, Stansfield, Nairn, Liu, Paluh, Yang, Dordick, Moremen, Linhardt: Structural remodeling of proteoglycans upon retinoic acid-induced differentiation of NCCIT cells. in Glycoconjugate journal 2013 (PubMed)
Human Monoclonal Biglycan Primary Antibody für IHC (p), IP - ABIN560056 : Zhang, Lee, Young, Wang: The Small Leucine-Rich Proteoglycan BGN Accumulates in CADASIL and Binds to NOTCH3. in Translational stroke research 2015 (PubMed)
Human Polyclonal Biglycan Primary Antibody für IHC, ELISA - ABIN334359 : Chen, Lenschow, Tiede, Fischer, Kalthoff, Ungefroren: Smad4/DPC4-dependent regulation of biglycan gene expression by transforming growth factor-beta in pancreatic tumor cells. in The Journal of biological chemistry 2002 (PubMed)
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Weitere Antikörper gegen Biglycan Interaktionspartner

Human Biglycan (BGN) Interaktionspartner

The differential immunoexpression of perlecan (zeige HSPG2 Antikörper) and biglycan in these types of ameloblastomas suggests their participation in the developmental process of these tumors.
TLR2 and BGN contribute to sterile inflammation and infertility in man.
Results show that Biglycan expression was upregulated by DNA demethylation in tumour endothelial cells from myeloma.
Elevated biglycan mRNA expression in adipose tissues of obese women
sex-specific allele combinations of BGN, COL5A1 (zeige COL5A1 Antikörper), and DCN (zeige DCN Antikörper), as well as eight miRNA recognition sequences, were associated with altered susceptibility to anterior cruciate ligament ruptures
high Bgn expression levels promote a more dense collagen architecture, leading to increased tissue stiffness. This increased tissue stiffness leads to higher integrin-beta1 expression on melanoma cells, which promotes their invasiveness.
The expression of hBGN in the skeletal muscle of the treated mice was 1.34-fold higher than that of the native mouse Bgn (mBgn). The low transduction efficiency and improved motor functions suggest that biglycan expressed in a small number of muscle fibers was likely to have been secreted and anchored to the cell surface throughout the whole muscular fibers
Results identified loss-of-function mutation in BGN gene in patients with an X-linked syndromic form of severe thoracic aortic aneurysms and dissections (TAAD) confirming BGN as causative gene in severe form of TAAD.
After the first year of smoking abstinence the levels of BGN expression and carotid-femoral pulse wave velocity are significantly improved as compared to baseline.
study reports a temporal relationship between altered placental biglycan expression and subsequent development of fetal growth restriction/small for gestational age.

Mouse (Murine) Biglycan (BGN) Interaktionspartner

Knockout results provide evidence that decorin (zeige DCN Antikörper) and biglycan are necessary for maintaining collagen fibril structure, fiber realignment, and mechanical properties of mature tendons.
A novel biological pathway has been discovered of soluble biglycan inducing HIF-2alpha (zeige EPAS1 Antikörper) protein stabilization and Epo (zeige EPO Antikörper) production presumably in an oxygen-independent manner, ultimately giving rise to secondary polycythemia.
Results show that Bgn plays a role in the process of angiogenesis during fracture healing, and that effect appears to be partially mediated through endostatin (zeige COL18A1 Antikörper) suppression.
Asporin (zeige ASPN Antikörper) deficiency changes skin glycosaminoglycan composition, and decorin (zeige DCN Antikörper) and biglycan content, which may explain the changes in skin mechanical properties.
Biglycan plays a protective role during the progression of atherosclerosis in ApoE (zeige APOE Antikörper)-deficient mice by inhibiting thrombin (zeige F2 Antikörper) generation.
These genes were concordantly induced by TAC (zeige IL2RA Antikörper) in WT but not in biglycan KO mice. CONCLUSIONS: Left ventricular pressure overload induces biglycan expression in cardiac fibroblasts. Ablation of biglycan improves cardiac function and attenuates left ventricular hypertrophy and fibrosis after long-term pressure overload.
Importance of biglycan and decorin (zeige DCN Antikörper) as targets for the manipulation of fetal membrane extracellular matrix stability in the context of inflammation.
Biglycan deficiency leads to loosely packed aortic collagen fibers, increased susceptibility of aortic elastin (zeige ELN Antikörper) fibers to angII-induced stress, and up-regulation of vascular perlecan (zeige HSPG2 Antikörper) content.
Biglycan signaling supported fetal membrane remodeling during early gestation in the absence of concomitant changes in TGFbeta (zeige TGFB1 Antikörper) levels.
Lumican (zeige LUM Antikörper) and biglycan influence corneal keratocyte lamellipodia organization and are critical in the regulation of stromal collagen fibrillogenesis.

Cow (Bovine) Biglycan (BGN) Interaktionspartner

Data show that biglycan, collagen type I, collagen type II, decorin (zeige DCN Antikörper), and versican (zeige Vcan Antikörper) were significantly affected by vibration duration, frequency, and amplitude.
biglycan showed a unique ability to organize collagen VI into extensive hexagonal-like networks over a time period of only a few minutes
biglycan-induced fibroblast cytoskeletal and signalling changes result in an increased cell migration; potential role in the remodelling process
The results indicate that CTGF (zeige CTGF Antikörper) suppresses the synthesis of biglycan but newly induced that of decorin (zeige DCN Antikörper) in the cells when the cell density is low.

Pig (Porcine) Biglycan (BGN) Interaktionspartner

LDL electrostatic interactions with decorin (zeige DCN Antikörper) and biglycan in the aortic valve leaflets and vascular wall is a major source of LDL retention.

Xenopus laevis Biglycan (BGN) Interaktionspartner

Bgn regulates BMP4 (zeige BMP4 Antikörper) signaling through modulation of Chordin (zeige CHRD Antikörper) anti-BMP4 (zeige BMP4 Antikörper) activity.

Rabbit Biglycan (BGN) Interaktionspartner

Biglycan (BGN) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The encoded protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein plays a role in assembly of collagen fibrils and muscle regeneration. It interacts with several proteins involved in muscular dystrophy, including alpha-dystroglycan, alpha- and gamma-sarcoglycan and collagen VI, and it is critical for the assembly of the dystrophin-associated protein complex.

Alternative names and synonyms associated with Biglycan (BGN)

biglycan (BGN) Antikörper
biglycan (Bgn) Antikörper
biglycan L homeolog (bgn.L) Antikörper
biglycan a (bgna) Antikörper
biglycan S homeolog (bgn.S) Antikörper
biglycan (bgn) Antikörper
biglycan b (bgnb) Antikörper

BG Antikörper
BGN Antikörper
BSPG1 Antikörper
DKFZp468I2427 Antikörper
dspg1 Antikörper
pg-s1 Antikörper
PGI Antikörper
slrr1a Antikörper
xbgn Antikörper
zgc:77123 Antikörper
zgc:91989 Antikörper

Bezeichner auf Proteinebene für anti-Biglycan (BGN) Antikörper

biglycan proteoglycan , bone/cartilage proteoglycan I , bone/cartilage proteoglycan-I , dermatan sulphate proteoglycan I , small leucine-rich protein 1A , PG-S1 , Small proteoglycan I (biglycan), bone (BSPG1) (bone/cartilage proteclycan 1 precursor) , bone/cartilage proteclycan 1 , leucine-rich PG I , biglycan

GENE ID	SPEZIES
633	Homo sapiens
12111	Mus musculus
25181	Rattus norvegicus
280733	Bos taurus
397396	Sus scrofa
399351	Xenopus laevis
403905	Canis lupus familiaris
431774	Danio rerio
443011	Ovis aries
444695	Xenopus laevis
473829	Pan troglodytes
697544	Macaca mulatta
780007	Xenopus (Silurana) tropicalis
792197	Danio rerio
100008663	Oryctolagus cuniculus
100033879	Equus caballus
100172504	Pongo abelii
100294505	Salmo salar
100590598	Nomascus leucogenys
100729862	Cavia porcellus

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Show all anti-Biglycan (BGN) Antikörper with Pubmed References