anti-GINS Complex Subunit 4 (Sld5 Homolog) (GINS4) Antikörper

Bezeichnung:: anti-GINS Complex Subunit 4 (Sld5 Homolog) Antikörper (GINS4)

Auf www.antikoerper-online.de finden Sie aktuell 25 GINS Complex Subunit 4 (Sld5 Homolog) (GINS4) Antikörper von 0 unterschiedlichen Herstellern. Insgesamt sind aktuell 40 GINS Complex Subunit 4 (Sld5 Homolog) Produkte verfügbar.

Synonyme:: 2810037c03rik, 4933405K01Rik, RGD1307397, Sld5

Alle Antikörper anzeigen	Gen	GeneID	UniProt
Anti-Human GINS4	GINS4	84296	Q9BRT9
Anti-Maus GINS4	GINS4	109145	Q99LZ3
Anti-Ratte GINS4	GINS4	290842	Q499W2
Weitere Synonyme anzeigen

Verknüpfte Pathways mit anti-GINS Complex Subunit 4 (Sld5 Homolog) Antikörper

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Weitere Antikörper gegen GINS Complex Subunit 4 (Sld5 Homolog) Interaktionspartner

Human GINS Complex Subunit 4 (Sld5 Homolog) (GINS4) Interaktionspartner

Knockdown of SLD5 using small interfering RNA resulted in reduction of cell growth both in vitro and an in vivo xenograft model. Moreover, we found that high levels of SLD5 in bladder cancer cells result from downregulation of microRNA (miR (zeige MLXIP Antikörper))-370 that otherwise suppresses its expression.
Sld5 a component of GINS complex interacts with SIK1 (zeige SIK1 Antikörper) and recruits it to the sites of DNA replication at the onset of S phase.
The C-terminal domains of the Sld5 and Psf1 (zeige TAP1 Antikörper) subunits are connected by linker regions to the core complex, and the C-terminal domain of Sld5 is important for core complex assembly.

Mouse (Murine) GINS Complex Subunit 4 (Sld5 Homolog) (GINS4) Interaktionspartner

Attenuation of SLD5 expression results in marked DNA damage in both normal cells and cancer cells, suggesting that it protects against DNA damage.
Requirement of SLD5 for early embryogenesis.
These data suggest that PSF1 (zeige TAP1 Antikörper) and SLD5 may cooperate in the proliferation of immature cell populations.

GINS Complex Subunit 4 (Sld5 Homolog) (GINS4) Antigen-Profil

Beschreibung des Gens

The yeast heterotetrameric GINS complex is made up of Sld5, Psf1 (GINS1\; MIM 610608), Psf2 (GINS2\; MIM 610609), and Psf3 (GINS3\; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005

Alternative names and synonyms associated with GINS Complex Subunit 4 (Sld5 Homolog) (GINS4)

GINS complex subunit 4 (GINS4) Antikörper
GINS complex subunit 4 (Sld5 homolog) (Gins4) Antikörper
GINS complex subunit 4 (Gins4) Antikörper

2810037c03rik Antikörper
4933405K01Rik Antikörper
RGD1307397 Antikörper
Sld5 Antikörper

Bezeichner auf Proteinebene für GINS4

DNA replication complex GINS protein SLD5 , SLD5 homolog , SLD5

GENE ID	SPEZIES
84296	Homo sapiens
109145	Mus musculus
290842	Rattus norvegicus
616799	Bos taurus

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