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Human Monoclonal LCN2 Primary Antibody für ELISA, WB - ABIN1045905
Devarajan: Neutrophil gelatinase-associated lipocalin (NGAL): a new marker of kidney disease. in Scandinavian journal of clinical and laboratory investigation. Supplementum 2008
Show all 18 Pubmed References
Human Monoclonal LCN2 Primary Antibody für ELISA, WB - ABIN1045904
Makris, Markou, Evodia, Dimopoulou, Drakopoulos, Ntetsika, Rizos, Baltopoulos, Haliassos: Urinary neutrophil gelatinase-associated lipocalin (NGAL) as an early marker of acute kidney injury in critically ill multiple trauma patients. in Clinical chemistry and laboratory medicine : CCLM / FESCC 2009
Show all 18 Pubmed References
Rat (Rattus) Polyclonal LCN2 Primary Antibody für IHC (p), WB - ABIN966671
Begley, Robb, Rockman, Visvader, Bockamp, Chan, Green: Structure of the gene encoding the murine SCL protein. in Gene 1994
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Human Polyclonal LCN2 Primary Antibody für IHC, IHC (p) - ABIN4331126
Rathore, Berard, Redensek, Chierzi, Lopez-Vales, Santos, Akira, David: Lipocalin 2 plays an immunomodulatory role and has detrimental effects after spinal cord injury. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2011
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Human Polyclonal LCN2 Primary Antibody für IF (p), IHC (p) - ABIN685627
Xing, Wang, Cheng, Montaner, Mandeville, Leung, van Leyen, Lok, Wang, Lo: Neuronal production of lipocalin-2 as a help-me signal for glial activation. in Stroke; a journal of cerebral circulation 2014
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Human Polyclonal LCN2 Primary Antibody für IHC (p), IHC - ABIN250360
Yu, Wu, Ping, Huang, Shen: NGAL can alternately mediate sunitinib resistance in renal cell carcinoma. in The Journal of urology 2014
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Human Polyclonal LCN2 Primary Antibody für IF (p) - ABIN908242
Xu, Zhang, Cheng, Liu, Zou, Zhan, Xiao, Xia: Transcription factor 7-like 1 dysregulates keratinocyte differentiation through upregulating lipocalin 2. in Cell death discovery 2016
Mouse (Murine) Polyclonal LCN2 Primary Antibody für ELISA, WB - ABIN408671
Venkatesha, Hanai, Seth, Karumanchi, Sukhatme: Lipocalin 2 antagonizes the proangiogenic action of ras in transformed cells. in Molecular cancer research : MCR 2006
Rat (Rattus) Monoclonal LCN2 Primary Antibody für ELISA, ICC - ABIN451573
Sultan, Ahmad, Rave-Fränk, Malik, Hess, Christiansen, Cameron: Induction of Lipocalin2 in a Rat Model of Lung Irradiation. in International journal of molecular sciences 2016
Urinary NGAL is a good predictor of mortality in established pediatric acute kidney injury (AKI) of heterogeneous etiology and outperforms calprotectin (zeige S100A8 Antikörper) and KIM-1 (zeige HAVCR1 Antikörper). Urinary calprotectin (zeige S100A8 Antikörper) and KIM-1 (zeige HAVCR1 Antikörper) predict renal replacement therapy requirement in pediatric AKI.
asma (zeige ACTA1 Antikörper) NGAL can be more useful than serum procalcitonin, C-reactive protein (zeige CRP Antikörper) , and white blood cell levels for identifying acute pyelonephritis in children with febrile urinary tract infections
These findings indicate that circulating levels of lipocalin-2 (LCN-2)in patients after acute pancreatitis may play a role in chronic low grade inflammation associated with abdominal adiposity.
Neutrophil gelatinase-associated lipocalin may play a dual role during tumorigenetic and developmental processes of endometrial carcinoma.
This study shows the find NGAL levels are significantly higher in regions throughout the brain which are commonly affected by AD pathology.
Through transcriptome profiling and combined gain- and loss-of-function studies, the authors identified LCN2 as a major downstream effector of TCF7L1 (zeige TCF3 Antikörper) that drives tumor growth.
Lipocalin 2 could facilitate proliferation of castration-resistant prostate cancer cells by activating androgen receptor (zeige AR Antikörper) transcriptional activity.
Urinary NGAL measured at ICU admission was significantly associated with long-term renal outcomes after hospital discharge in MAKE-free ICU survivors. Urinary NGAL measurements at ICU might be useful to identify a high risk population of kidney disease progression after intensive care.
Recent evidence supports the existence of transferrin (zeige Tf Antikörper)-independent iron transport mechanisms in the tumor microenvironment, which points to local iron transport proteins such as lipocalin-2 and/or low molecular weight iron-trafficking substances such as siderophores. [review]
Urinary NGAL might play role in the pathway of renal tubular damage in patients with autosomal-dominant polycystic kidney disease
Lipocalin-2 from both myeloid cells and the epithelium combats Klebsiella pneumoniae lung infection in mice.
IL-1beta (zeige IL1B Antikörper) has a direct effect on NGAL production by tubular epithelial cells.
Knockout of Lcn2 attenuated tumor-associated lymphangiogenesis and breast tumor metastasis
Overexpression of exogenous kidney-specific Ngal reduced cystic progression and prolonged the lifespan in polycystic kidney disease mice, and was associated with reductions in interstitial fibrosis and proliferation, and augmented apoptosis.
Either Lcn2 deficiency or anti-Lcn2 antibody blockade limits abdominal aortic aneurysm expansion in mice by decreasing neutrophil infiltration in the aorta.
Results suggest that blood brain barrier leakage occurs in white matter after subarachnoid hemorrhage (SAH (zeige ACSM3 Antikörper)) and that LCN2 contributes to SAH (zeige ACSM3 Antikörper)-induced blood brain barrier disruption.
LCN2 overexpression in bones modifies the bone marrow microenvironment via modulation of the expression of key secreted factors and cytokines, which in turn regulate the hematopoietic stem cell niche behavior enhancing both HSC (zeige FUT1 Antikörper) homing in young mice and erythrocytes production in older mice.
LCN2 modulated the secretion of proinflammatory cytokines in PSC of the PDAC tumor microenvironment, whereas downregulation of LCN2-specific receptor SLC22A17 (zeige SLC22A17 Antikörper) blocked these effects. Our results reveal how LCN2 acts in the tumor microenvironment links obesity, inflammation, and PDAC development.
results identify lipocalin 2 as a bone-derived hormone with metabolic regulatory effects, which suppresses appetite in a MC4R (zeige MC4R Antikörper)-dependent manner, and show that the control of appetite is an endocrine function of bone
Lcn2 can suppress the beneficial cardiac autophagic response to ischemia and that this contributes to enhanced ischemia-induced cell death and cardiac dysfunction.
we demonstrated the presence of high molecular weight (HMW) complexes (130, 170, and 220 kDa) containing MMP9 (zeige MMP9 Antikörper), TIMP1 (zeige TIMP1 Antikörper), and NGAL (also MMP2 (zeige MMP2 Antikörper) in 220 kDa complex) without proteolytic activity.
porcine p25alpha (zeige Tppp Antikörper) is heavily modified with a variety of modifications: phosphorylation, di- and trimethylation, citrullination and a HexNAc group.
mouse homolog plays a role in IL3 withdrawal-induced apoptosis
, lipocalin 2 (oncogene 24p3)
, 25 kDa alpha-2-microglobulin-related subunit of MMP-9
, migration-stimulating factor inhibitor
, neutrophil gelatinase-associated lipocalin
, oncogene 24p3
, siderocalin LCN2
, SV-40-induced 24P3 protein
, secreted inducible protein 24
, alpha-2-microglobulin-related protein
, alpha-2U globulin-related protein