Protein Überblick

Transcription factor involved in the regulation of the insulin signaling pathway. Consistently activates both the downstream target Thor\d4EBP and the feedback control target InR. Involved in negative regulation of the cell cycle, modulating cell growth and proliferation. In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor. Foxo activated in the adult fat body can regulate lifespan in adults\; an insulin peptide itself may function as one secondary messenger of insulin-regulated aging. Also regulates Lip4, homolog of human acid lipases, thereby acting as a key modulator of lipid metabolism by insulin signaling and integrates insulin responses to glucose and lipid homeostasis.

Alternative names and synonyms associated with FOXO

• forkhead box, sub-group O (foxo) Antikörper

• 3143 Antikörper
• Afx Antikörper
• anon-WO0118547.374 Antikörper
• cg3143 Antikörper
• dfoxo Antikörper
• Alle Synonyme
• Dmel\\CG3143 Antikörper
• DmQ95V5 Antikörper
• fd88A Antikörper
• FKHR Antikörper
• foxo Antikörper
• Q95V55 Antikörper

Bezeichner auf Proteinebene für FOXO

CG3143-PB , CG3143-PC , CG3143-PF , CG3143-PG , forkhead Box O , forkhead bOX-containing protein, subfamily O , forkhead box , forkhead box sub-group O , forkhead box type O , forkhead box, subgroup O , forkhead transcription factor , foxo-PB , foxo-PC , foxo-PF , foxo-PG